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Page 1
Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice.
Spix B, Butz ES, Chen CC, Rosato AS, Tang R, Jeridi A, Kudrina V, Plesch E, Wartenberg P, Arlt E, Briukhovetska D, Ansari M, Günsel GG, Conlon TM, Wyatt A, Wetzel S, Teupser D, Holdt LM, Ectors F, Boekhoff I, Boehm U, García-Añoveros J, Saftig P, Giera M, Kobold S, Schiller HB, Zierler S, Gudermann T, Wahl-Schott C, Bracher F, Yildirim AÖ, Biel M, Grimm C. Spix B, et al. Nat Commun. 2022 Jan 14;13(1):318. doi: 10.1038/s41467-021-27860-x. Nat Commun. 2022. PMID: 35031603 Free PMC article.
Endolysosomal Cation Channels and Lung Disease.
Spix B, Jeridi A, Ansari M, Yildirim AÖ, Schiller HB, Grimm C. Spix B, et al. Cells. 2022 Jan 17;11(2):304. doi: 10.3390/cells11020304. Cells. 2022. PMID: 35053420 Free PMC article. Review.
TRPML Cation Channels in Inflammation and Immunity.
Spix B, Chao YK, Abrahamian C, Chen CC, Grimm C. Spix B, et al. Front Immunol. 2020 Feb 28;11:225. doi: 10.3389/fimmu.2020.00225. eCollection 2020. Front Immunol. 2020. PMID: 32184778 Free PMC article. Review.
TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann-Pick type C1, and Batten disease.
Scotto Rosato A, Krogsaeter EK, Jaślan D, Abrahamian C, Montefusco S, Soldati C, Spix B, Pizzo MT, Grieco G, Böck J, Wyatt A, Wünkhaus D, Passon M, Stieglitz M, Keller M, Hermey G, Markmann S, Gruber-Schoffnegger D, Cotman S, Johannes L, Crusius D, Boehm U, Wahl-Schott C, Biel M, Bracher F, De Leonibus E, Polishchuk E, Medina DL, Paquet D, Grimm C. Scotto Rosato A, et al. Among authors: spix b. EMBO Mol Med. 2022 Sep 7;14(9):e15377. doi: 10.15252/emmm.202115377. Epub 2022 Aug 5. EMBO Mol Med. 2022. PMID: 35929194 Free PMC article.
P-selectin-dependent leukocyte adhesion is governed by endolysosomal two-pore channel 2.
Goretzko J, Pauels I, Heitzig N, Thomas K, Kardell M, Naß J, Krogsaeter EK, Schloer S, Spix B, Linard Matos AL, Leser C, Wegner T, Glorius F, Bracher F, Gerke V, Rossaint J, Grimm C, Rescher U. Goretzko J, et al. Among authors: spix b. Cell Rep. 2023 Dec 26;42(12):113501. doi: 10.1016/j.celrep.2023.113501. Epub 2023 Nov 30. Cell Rep. 2023. PMID: 38039128 Free article.
Endolysosomal TPCs regulate social behavior by controlling oxytocin secretion.
Martucci LL, Launay JM, Kawakami N, Sicard C, Desvignes N, Dakouane-Giudicelli M, Spix B, Têtu M, Gilmaire FO, Paulcan S, Callebert J, Vaillend C, Bracher F, Grimm C, Fossier P, de la Porte S, Sakamoto H, Morris J, Galione A, Granon S, Cancela JM. Martucci LL, et al. Among authors: spix b. Proc Natl Acad Sci U S A. 2023 Feb 14;120(7):e2213682120. doi: 10.1073/pnas.2213682120. Epub 2023 Feb 6. Proc Natl Acad Sci U S A. 2023. PMID: 36745816 Free PMC article.