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Systemic immunity in cancer.
Hiam-Galvez KJ, Allen BM, Spitzer MH. Hiam-Galvez KJ, et al. Among authors: spitzer mh. Nat Rev Cancer. 2021 Jun;21(6):345-359. doi: 10.1038/s41568-021-00347-z. Epub 2021 Apr 9. Nat Rev Cancer. 2021. PMID: 33837297 Free PMC article. Review.
Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity.
Carmi Y, Spitzer MH, Linde IL, Burt BM, Prestwood TR, Perlman N, Davidson MG, Kenkel JA, Segal E, Pusapati GV, Bhattacharya N, Engleman EG. Carmi Y, et al. Among authors: spitzer mh. Nature. 2015 May 7;521(7550):99-104. doi: 10.1038/nature14424. Epub 2015 Apr 29. Nature. 2015. PMID: 25924063 Free PMC article.
Systemic Immunity Is Required for Effective Cancer Immunotherapy.
Spitzer MH, Carmi Y, Reticker-Flynn NE, Kwek SS, Madhireddy D, Martins MM, Gherardini PF, Prestwood TR, Chabon J, Bendall SC, Fong L, Nolan GP, Engleman EG. Spitzer MH, et al. Cell. 2017 Jan 26;168(3):487-502.e15. doi: 10.1016/j.cell.2016.12.022. Epub 2017 Jan 19. Cell. 2017. PMID: 28111070 Free PMC article.
Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity.
Zammit NW, Siggs OM, Gray PE, Horikawa K, Langley DB, Walters SN, Daley SR, Loetsch C, Warren J, Yap JY, Cultrone D, Russell A, Malle EK, Villanueva JE, Cowley MJ, Gayevskiy V, Dinger ME, Brink R, Zahra D, Chaudhri G, Karupiah G, Whittle B, Roots C, Bertram E, Yamada M, Jeelall Y, Enders A, Clifton BE, Mabbitt PD, Jackson CJ, Watson SR, Jenne CN, Lanier LL, Wiltshire T, Spitzer MH, Nolan GP, Schmitz F, Aderem A, Porebski BT, Buckle AM, Abbott DW, Ziegler JB, Craig ME, Benitez-Aguirre P, Teo J, Tangye SG, King C, Wong M, Cox MP, Phung W, Tang J, Sandoval W, Wertz IE, Christ D, Goodnow CC, Grey ST. Zammit NW, et al. Among authors: spitzer mh. Nat Immunol. 2019 Oct;20(10):1299-1310. doi: 10.1038/s41590-019-0492-0. Epub 2019 Sep 18. Nat Immunol. 2019. PMID: 31534238
Depletion of microbiome-derived molecules in the host using Clostridium genetics.
Guo CJ, Allen BM, Hiam KJ, Dodd D, Van Treuren W, Higginbottom S, Nagashima K, Fischer CR, Sonnenburg JL, Spitzer MH, Fischbach MA. Guo CJ, et al. Among authors: spitzer mh. Science. 2019 Dec 13;366(6471):eaav1282. doi: 10.1126/science.aav1282. Science. 2019. PMID: 31831639 Free PMC article.
Tumor Immune Profiling-Based Neoadjuvant Immunotherapy for Locally Advanced Melanoma.
Levine LS, Mahuron KM, Tsai KK, Wu C, Mattis DM, Pauli ML, Oglesby A, Lee JC, Spitzer MH, Krummel MF, Algazi AP, Rosenblum MD, Alvarado M, Daud AI. Levine LS, et al. Among authors: spitzer mh. Ann Surg Oncol. 2020 Oct;27(11):4122-4130. doi: 10.1245/s10434-020-08648-7. Epub 2020 Jun 2. Ann Surg Oncol. 2020. PMID: 32488521 Free PMC article.
Intratumoral CD4+ T Cells Mediate Anti-tumor Cytotoxicity in Human Bladder Cancer.
Oh DY, Kwek SS, Raju SS, Li T, McCarthy E, Chow E, Aran D, Ilano A, Pai CS, Rancan C, Allaire K, Burra A, Sun Y, Spitzer MH, Mangul S, Porten S, Meng MV, Friedlander TW, Ye CJ, Fong L. Oh DY, et al. Among authors: spitzer mh. Cell. 2020 Jun 25;181(7):1612-1625.e13. doi: 10.1016/j.cell.2020.05.017. Epub 2020 Jun 3. Cell. 2020. PMID: 32497499 Free PMC article.
Pre-existing immune status associated with response to combination of sipuleucel-T and ipilimumab in patients with metastatic castration-resistant prostate cancer.
Sinha M, Zhang L, Subudhi S, Chen B, Marquez J, Liu EV, Allaire K, Cheung A, Ng S, Nguyen C, Friedlander TW, Aggarwal R, Spitzer M, Allison JP, Small EJ, Sharma P, Fong L. Sinha M, et al. J Immunother Cancer. 2021 May;9(5):e002254. doi: 10.1136/jitc-2020-002254. J Immunother Cancer. 2021. PMID: 33986125 Free PMC article. Clinical Trial.
75 results