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Avasopasem manganese (GC4419) protects against cisplatin-induced chronic kidney disease: An exploratory analysis of renal metrics from a randomized phase 2b clinical trial in head and neck cancer patients.
Mapuskar KA, Vasquez Martinez G, Pulliam CF, Petronek MS, Steinbach EJ, Monga V, Furqan M, Jetton JG, Saunders DP, Pearce A, Davidson S, Pitre L, Dunlap NE, Fairbanks R, Lee CM, Mott SL, Bodeker KL, Cl H, Buatti JM, Anderson CM, Beardsley RA, Holmlund JT, Zepeda-Orozco D, Spitz DR, Allen BG. Mapuskar KA, et al. Among authors: spitz dr. Redox Biol. 2023 Apr;60:102599. doi: 10.1016/j.redox.2022.102599. Epub 2023 Jan 3. Redox Biol. 2023. PMID: 36640725 Free PMC article. Clinical Trial.
Tubular Mitochondrial Pyruvate Carrier Disruption Elicits Redox Adaptations that Protect from Acute Kidney Injury.
Rauckhorst AJ, Martinez GV, Andrade GM, Wen H, Kim JY, Simoni A, Mapuskar KA, Rastogi P, Steinbach EJ, McCormick ML, Allen BG, Pabla NS, Jackson AR, Coleman MC, Spitz DR, Taylor EB, Zepeda-Orozco D. Rauckhorst AJ, et al. Among authors: spitz dr. bioRxiv [Preprint]. 2023 Jan 31:2023.01.31.526492. doi: 10.1101/2023.01.31.526492. bioRxiv. 2023. PMID: 36778297 Free PMC article. Updated. Preprint.
Magnetite nanoparticles as a kinetically favorable source of iron to enhance GBM response to chemoradiosensitization with pharmacological ascorbate.
Petronek MS, Teferi N, Caster JM, Stolwijk JM, Zaher A, Buatti JM, Hasan D, Wafa EI, Salem AK, Gillan EG, St-Aubin JJ, Buettner GR, Spitz DR, Magnotta VA, Allen BG. Petronek MS, et al. Among authors: spitz dr. Redox Biol. 2023 Jun;62:102651. doi: 10.1016/j.redox.2023.102651. Epub 2023 Mar 7. Redox Biol. 2023. PMID: 36924683 Free PMC article.
Auranofin Inhibition of Thioredoxin Reductase Sensitizes Lung Neuroendocrine Tumor Cells (NETs) and Small Cell Lung Cancer (SCLC) Cells to Sorafenib as well as Inhibiting SCLC Xenograft Growth.
Johnson SS, Liu D, Ewald JT, Robles-Planells C, Christensen KA, Bayanbold K, Wels BR, Solst SR, O'Dorisio MS, Allen BG, Menda Y, Spitz DR, Fath MA. Johnson SS, et al. Among authors: spitz dr. bioRxiv [Preprint]. 2024 Jan 30:2023.05.07.539772. doi: 10.1101/2023.05.07.539772. bioRxiv. 2024. PMID: 37215042 Free PMC article. Preprint.
Redox Regulation of Nrf2 in Cisplatin-Induced Kidney Injury.
Mapuskar KA, Pulliam CF, Zepeda-Orozco D, Griffin BR, Furqan M, Spitz DR, Allen BG. Mapuskar KA, et al. Among authors: spitz dr. Antioxidants (Basel). 2023 Sep 6;12(9):1728. doi: 10.3390/antiox12091728. Antioxidants (Basel). 2023. PMID: 37760031 Free PMC article. Review.
Depletion of Labile Iron Induces Replication Stress and Enhances Responses to Chemoradiation in Non-Small-Cell Lung Cancer.
Bayanbold K, Singhania M, Fath MA, Searby CC, Stolwijk JM, Henrich JB, Pulliam CF, Schoenfeld JD, Mapuskar KA, Sho S, Caster JM, Allen BG, Buettner GR, Spies M, Goswami PC, Petronek MS, Spitz DR. Bayanbold K, et al. Among authors: spitz dr. Antioxidants (Basel). 2023 Nov 15;12(11):2005. doi: 10.3390/antiox12112005. Antioxidants (Basel). 2023. PMID: 38001858 Free PMC article.
Tubular mitochondrial pyruvate carrier disruption elicits redox adaptations that protect from acute kidney injury.
Rauckhorst AJ, Vasquez Martinez G, Mayoral Andrade G, Wen H, Kim JY, Simoni A, Robles-Planells C, Mapuskar KA, Rastogi P, Steinbach EJ, McCormick ML, Allen BG, Pabla NS, Jackson AR, Coleman MC, Spitz DR, Taylor EB, Zepeda-Orozco D. Rauckhorst AJ, et al. Among authors: spitz dr. Mol Metab. 2024 Jan;79:101849. doi: 10.1016/j.molmet.2023.101849. Epub 2023 Dec 7. Mol Metab. 2024. PMID: 38056691 Free PMC article.
291 results