Spirig R - Search Results

1

Mechanism of increased efficacy of recombinant Fc-μTP-L309C compared to IVIg to ameliorate mouse immune thrombocytopenia.

Lewis BJB, Binnington B, Blacquiere M, Spirig R, Käsermann F, Branch DR. Lewis BJB, et al. Among authors: spirig r. EJHaem. 2021 Sep 29;2(4):789-793. doi: 10.1002/jha2.304. eCollection 2021 Nov. EJHaem. 2021. PMID: 35845218 Free PMC article.

2

IVIG in autoimmune disease - Potential next generation biologics.

Zuercher AW, Spirig R, Baz Morelli A, Käsermann F. Zuercher AW, et al. Among authors: spirig r. Autoimmun Rev. 2016 Aug;15(8):781-5. doi: 10.1016/j.autrev.2016.03.018. Epub 2016 Mar 25. Autoimmun Rev. 2016. PMID: 27019051 Review.

3

rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and FcγRs.

Spirig R, Campbell IK, Koernig S, Chen CG, Lewis BJB, Butcher R, Muir I, Taylor S, Chia J, Leong D, Simmonds J, Scotney P, Schmidt P, Fabri L, Hofmann A, Jordi M, Spycher MO, Cattepoel S, Brasseit J, Panousis C, Rowe T, Branch DR, Baz Morelli A, Käsermann F, Zuercher AW. Spirig R, et al. J Immunol. 2018 Apr 15;200(8):2542-2553. doi: 10.4049/jimmunol.1701171. Epub 2018 Mar 12. J Immunol. 2018. PMID: 29531170 Free PMC article.

4

Next-generation Fc receptor-targeting biologics for autoimmune diseases.

Zuercher AW, Spirig R, Baz Morelli A, Rowe T, Käsermann F. Zuercher AW, et al. Among authors: spirig r. Autoimmun Rev. 2019 Oct;18(10):102366. doi: 10.1016/j.autrev.2019.102366. Epub 2019 Aug 9. Autoimmun Rev. 2019. PMID: 31404703 Free article. Review.

5

Using the K/BxN mouse model of endogenous, chronic, rheumatoid arthritis for the evaluation of potential immunoglobulin-based therapeutic agents, including IVIg and Fc-μTP-L309C, a recombinant IgG1 Fc hexamer.

Lewis BJB, Ville J, Blacquiere M, Cen S, Spirig R, Zuercher AW, Käsermann F, Branch DR. Lewis BJB, et al. Among authors: spirig r. BMC Immunol. 2019 Dec 4;20(1):44. doi: 10.1186/s12865-019-0328-6. BMC Immunol. 2019. PMID: 31801459 Free PMC article.

6

Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis.

Almizraq RJ, Frias Boligan K, Lewis BJB, Cen S, Whetstone H, Spirig R, Käsermann F, Campbell IK, von Gunten S, Branch DR. Almizraq RJ, et al. Among authors: spirig r. Pharmacology. 2023;108(2):176-187. doi: 10.1159/000528780. Epub 2023 Jan 25. Pharmacology. 2023. PMID: 36696888 Free PMC article.

7

Recombinant IgG1 Fc hexamers block cytotoxicity and pathological changes in experimental in vitro and rat models of neuromyelitis optica.

Tradtrantip L, Felix CM, Spirig R, Morelli AB, Verkman AS. Tradtrantip L, et al. Among authors: spirig r. Neuropharmacology. 2018 May 1;133:345-353. doi: 10.1016/j.neuropharm.2018.02.002. Epub 2018 Feb 8. Neuropharmacology. 2018. PMID: 29428821 Free PMC article.

8

Small-Molecule Immunosuppressive Drugs and Therapeutic Immunoglobulins Differentially Inhibit NK Cell Effector Functions in vitro.

Pradier A, Papaserafeim M, Li N, Rietveld A, Kaestel C, Gruaz L, Vonarburg C, Spirig R, Puga Yung GL, Seebach JD. Pradier A, et al. Among authors: spirig r. Front Immunol. 2019 Mar 27;10:556. doi: 10.3389/fimmu.2019.00556. eCollection 2019. Front Immunol. 2019. PMID: 30972058 Free PMC article.

9

The complement inhibitor low molecular weight dextran sulfate prevents TLR4-induced phenotypic and functional maturation of human dendritic cells.

Spirig R, van Kooten C, Obregon C, Nicod L, Daha M, Rieben R. Spirig R, et al. J Immunol. 2008 Jul 15;181(2):878-90. doi: 10.4049/jimmunol.181.2.878. J Immunol. 2008. PMID: 18606639

10

Reconstituted high-density lipoprotein modulates activation of human leukocytes.

Spirig R, Schaub A, Kropf A, Miescher S, Spycher MO, Rieben R. Spirig R, et al. PLoS One. 2013 Aug 14;8(8):e71235. doi: 10.1371/journal.pone.0071235. eCollection 2013. PLoS One. 2013. PMID: 23967171 Free PMC article.

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