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Aralar Sequesters GABA into Hyperactive Mitochondria, Causing Social Behavior Deficits.
Kanellopoulos AK, Mariano V, Spinazzi M, Woo YJ, McLean C, Pech U, Li KW, Armstrong JD, Giangrande A, Callaerts P, Smit AB, Abrahams BS, Fiala A, Achsel T, Bagni C. Kanellopoulos AK, et al. Among authors: spinazzi m. Cell. 2020 Mar 19;180(6):1178-1197.e20. doi: 10.1016/j.cell.2020.02.044. Cell. 2020. PMID: 32200800 Free article.
Deficiency of the miR-29a/b-1 cluster leads to ataxic features and cerebellar alterations in mice.
Papadopoulou AS, Serneels L, Achsel T, Mandemakers W, Callaerts-Vegh Z, Dooley J, Lau P, Ayoubi T, Radaelli E, Spinazzi M, Neumann M, Hébert SS, Silahtaroglu A, Liston A, D'Hooge R, Glatzel M, De Strooper B. Papadopoulou AS, et al. Among authors: spinazzi m. Neurobiol Dis. 2015 Jan;73:275-88. doi: 10.1016/j.nbd.2014.10.006. Epub 2014 Oct 12. Neurobiol Dis. 2015. PMID: 25315682
PARL: The mitochondrial rhomboid protease.
Spinazzi M, De Strooper B. Spinazzi M, et al. Semin Cell Dev Biol. 2016 Dec;60:19-28. doi: 10.1016/j.semcdb.2016.07.034. Epub 2016 Aug 5. Semin Cell Dev Biol. 2016. PMID: 27502471 Review.
Spontaneous Incidental Brain Lesions in C57BL/6J Mice.
Tarrant JC, Savickas P, Omodho L, Spinazzi M, Radaelli E. Tarrant JC, et al. Among authors: spinazzi m. Vet Pathol. 2020 Jan;57(1):172-182. doi: 10.1177/0300985819859878. Epub 2019 Jul 4. Vet Pathol. 2020. PMID: 31272300
Melanoma addiction to the long non-coding RNA SAMMSON.
Leucci E, Vendramin R, Spinazzi M, Laurette P, Fiers M, Wouters J, Radaelli E, Eyckerman S, Leonelli C, Vanderheyden K, Rogiers A, Hermans E, Baatsen P, Aerts S, Amant F, Van Aelst S, van den Oord J, de Strooper B, Davidson I, Lafontaine DL, Gevaert K, Vandesompele J, Mestdagh P, Marine JC. Leucci E, et al. Among authors: spinazzi m. Nature. 2016 Mar 24;531(7595):518-22. doi: 10.1038/nature17161. Nature. 2016. PMID: 27008969
A novel deletion in the GTPase domain of OPA1 causes defects in mitochondrial morphology and distribution, but not in function.
Spinazzi M, Cazzola S, Bortolozzi M, Baracca A, Loro E, Casarin A, Solaini G, Sgarbi G, Casalena G, Cenacchi G, Malena A, Frezza C, Carrara F, Angelini C, Scorrano L, Salviati L, Vergani L. Spinazzi M, et al. Hum Mol Genet. 2008 Nov 1;17(21):3291-302. doi: 10.1093/hmg/ddn225. Epub 2008 Aug 4. Hum Mol Genet. 2008. PMID: 18678599
52 results