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Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages.
Cell Metab. 2022 Mar 1;34(3):487-501.e8. doi: 10.1016/j.cmet.2022.02.002.
Cell Metab. 2022.
PMID: 35235776
Free article.
Utilizing a human TLR selective ligand in a humanized immune system mouse model to investigate human TLR4 signaling.
Twomey R, Graham S, Spina JS, Wu X, Dubé PE, Ferrebee C, Housley W.
Twomey R, et al. Among authors: spina js.
J Biol Methods. 2023 Nov 20;10:jbm-10-e99010008. doi: 10.14440/jbm.2023.408. eCollection 2023.
J Biol Methods. 2023.
PMID: 38046987
Free PMC article.
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The Doubletime Homolog KIN-20 Mainly Regulates let-7 Independently of Its Effects on the Period Homolog LIN-42 in Caenorhabditis elegans.
Rhodehouse K, Cascino K, Aseltine L, Padula A, Weinstein R, Spina JS, Olivero CE, Van Wynsberghe PM.
Rhodehouse K, et al. Among authors: spina js.
G3 (Bethesda). 2018 Jul 31;8(8):2617-2629. doi: 10.1534/g3.118.200392.
G3 (Bethesda). 2018.
PMID: 29880558
Free PMC article.
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SinR is a mutational target for fine-tuning biofilm formation in laboratory-evolved strains of Bacillus subtilis.
Leiman SA, Arboleda LC, Spina JS, McLoon AL.
Leiman SA, et al. Among authors: spina js.
BMC Microbiol. 2014 Nov 30;14:301. doi: 10.1186/s12866-014-0301-8.
BMC Microbiol. 2014.
PMID: 25433524
Free PMC article.
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