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Development of 2-Methoxyhuprine as Novel Lead for Alzheimer's Disease Therapy.
Mezeiova E, Korabecny J, Sepsova V, Hrabinova M, Jost P, Muckova L, Kucera T, Dolezal R, Misik J, Spilovska K, Pham NL, Pokrievkova L, Roh J, Jun D, Soukup O, Kaping D, Kuca K. Mezeiova E, et al. Among authors: spilovska k. Molecules. 2017 Jul 28;22(8):1265. doi: 10.3390/molecules22081265. Molecules. 2017. PMID: 28788095 Free PMC article.
The concept of hybrid molecules of tacrine and benzyl quinolone carboxylic acid (BQCA) as multifunctional agents for Alzheimer's disease.
Hepnarova V, Korabecny J, Matouskova L, Jost P, Muckova L, Hrabinova M, Vykoukalova N, Kerhartova M, Kucera T, Dolezal R, Nepovimova E, Spilovska K, Mezeiova E, Pham NL, Jun D, Staud F, Kaping D, Kuca K, Soukup O. Hepnarova V, et al. Among authors: spilovska k. Eur J Med Chem. 2018 Apr 25;150:292-306. doi: 10.1016/j.ejmech.2018.02.083. Epub 2018 Mar 2. Eur J Med Chem. 2018. PMID: 29533874
From pyridinium-based to centrally active acetylcholinesterase reactivators.
Korabecny J, Soukup O, Dolezal R, Spilovska K, Nepovimova E, Andrs M, Nguyen TD, Jun D, Musilek K, Kucerova-Chlupacova M, Kuca K. Korabecny J, et al. Among authors: spilovska k. Mini Rev Med Chem. 2014;14(3):215-21. doi: 10.2174/1389557514666140219103138. Mini Rev Med Chem. 2014. PMID: 24552265 Review.
7-MEOTA-donepezil like compounds as cholinesterase inhibitors: Synthesis, pharmacological evaluation, molecular modeling and QSAR studies.
Korabecny J, Dolezal R, Cabelova P, Horova A, Hruba E, Ricny J, Sedlacek L, Nepovimova E, Spilovska K, Andrs M, Musilek K, Opletalova V, Sepsova V, Ripova D, Kuca K. Korabecny J, et al. Among authors: spilovska k. Eur J Med Chem. 2014 Jul 23;82:426-38. doi: 10.1016/j.ejmech.2014.05.066. Epub 2014 May 27. Eur J Med Chem. 2014. PMID: 24929293
15 results