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Alisertib (MLN8237) an investigational agent suppresses Aurora A and B activity, inhibits proliferation, promotes endo-reduplication and induces apoptosis in T-NHL cell lines supporting its importance in PTCL treatment.
Qi W, Spier C, Liu X, Agarwal A, Cooke LS, Persky DO, Chen D, Miller TP, Mahadevan D. Qi W, et al. Among authors: spier c. Leuk Res. 2013 Apr;37(4):434-9. doi: 10.1016/j.leukres.2012.10.017. Epub 2012 Nov 12. Leuk Res. 2013. PMID: 23153524 Free PMC article.
NCAM (CD56)-positive malignant lymphoma.
Kern WF, Spier CM, Miller TP, Grogan TM. Kern WF, et al. Among authors: spier cm. Leuk Lymphoma. 1993 Dec;12(1-2):1-10. doi: 10.3109/10428199309059565. Leuk Lymphoma. 1993. PMID: 7512851 Review.
Burkitt's-like lymphoma of T-cell type.
Oliver JD, Grogan TM, Payne CM, Spier C, Richter LC, Rangel CS. Oliver JD, et al. Among authors: spier c. Mod Pathol. 1988 Jan;1(1):15-22. Mod Pathol. 1988. PMID: 3266334
Immunotherapy of advanced malignancy by direct gene transfer of an interleukin-2 DNA/DMRIE/DOPE lipid complex: phase I/II experience.
Galanis E, Hersh EM, Stopeck AT, Gonzalez R, Burch P, Spier C, Akporiaye ET, Rinehart JJ, Edmonson J, Sobol RE, Forscher C, Sondak VK, Lewis BD, Unger EC, O'Driscoll M, Selk L, Rubin J. Galanis E, et al. Among authors: spier c. J Clin Oncol. 1999 Oct;17(10):3313-23. doi: 10.1200/JCO.1999.17.10.3313. J Clin Oncol. 1999. PMID: 10506635 Clinical Trial.
124 results