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A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites.
Birnbaum J, Scharf S, Schmidt S, Jonscher E, Hoeijmakers WAM, Flemming S, Toenhake CG, Schmitt M, Sabitzki R, Bergmann B, Fröhlke U, Mesén-Ramírez P, Blancke Soares A, Herrmann H, Bártfai R, Spielmann T. Birnbaum J, et al. Among authors: spielmann t. Science. 2020 Jan 3;367(6473):51-59. doi: 10.1126/science.aax4735. Science. 2020. PMID: 31896710
Imaging of live malaria blood stage parasites.
Grüring C, Spielmann T. Grüring C, et al. Among authors: spielmann t. Methods Enzymol. 2012;506:81-92. doi: 10.1016/B978-0-12-391856-7.00029-9. Methods Enzymol. 2012. PMID: 22341220
Uncovering common principles in protein export of malaria parasites.
Grüring C, Heiber A, Kruse F, Flemming S, Franci G, Colombo SF, Fasana E, Schoeler H, Borgese N, Stunnenberg HG, Przyborski JM, Gilberger TW, Spielmann T. Grüring C, et al. Among authors: spielmann t. Cell Host Microbe. 2012 Nov 15;12(5):717-29. doi: 10.1016/j.chom.2012.09.010. Cell Host Microbe. 2012. PMID: 23159060 Free article.
Identification of new PNEPs indicates a substantial non-PEXEL exportome and underpins common features in Plasmodium falciparum protein export.
Heiber A, Kruse F, Pick C, Grüring C, Flemming S, Oberli A, Schoeler H, Retzlaff S, Mesén-Ramírez P, Hiss JA, Kadekoppala M, Hecht L, Holder AA, Gilberger TW, Spielmann T. Heiber A, et al. Among authors: spielmann t. PLoS Pathog. 2013;9(8):e1003546. doi: 10.1371/journal.ppat.1003546. Epub 2013 Aug 8. PLoS Pathog. 2013. PMID: 23950716 Free PMC article.
Pellicle formation in the malaria parasite.
Kono M, Heincke D, Wilcke L, Wong TW, Bruns C, Herrmann S, Spielmann T, Gilberger TW. Kono M, et al. Among authors: spielmann t. J Cell Sci. 2016 Feb 15;129(4):673-80. doi: 10.1242/jcs.181230. Epub 2016 Jan 13. J Cell Sci. 2016. PMID: 26763910 Free PMC article.
Export of malaria proteins requires co-translational processing of the PEXEL motif independent of phosphatidylinositol-3-phosphate binding.
Boddey JA, O'Neill MT, Lopaticki S, Carvalho TG, Hodder AN, Nebl T, Wawra S, van West P, Ebrahimzadeh Z, Richard D, Flemming S, Spielmann T, Przyborski J, Babon JJ, Cowman AF. Boddey JA, et al. Among authors: spielmann t. Nat Commun. 2016 Feb 1;7:10470. doi: 10.1038/ncomms10470. Nat Commun. 2016. PMID: 26832821 Free PMC article.
87 results