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Open letter: Selection of a new Executive Director of the European Chemicals Agency (ECHA) provides an opportunity for the EU to lead in the field of chemicals management and implementation of innovative science.
Seidle T, Kandarova H, Hartung T, Leist M, Neuhaus W, Spielmann H, Rovida C. Seidle T, et al. Among authors: spielmann h. ALTEX. 2021 Oct 27. doi: 10.14573/altex.2110271. Online ahead of print. ALTEX. 2021. PMID: 34706053 Free article. No abstract available.
The sophisticated process of validation.
Hartung T, Spielmann H. Hartung T, et al. Among authors: spielmann h. ALTEX. 1995;12(2):98-103. ALTEX. 1995. PMID: 11178424 English.
The Rise of Three Rs Centres and Platforms in Europe.
Neuhaus W, Reininger-Gutmann B, Rinner B, Plasenzotti R, Wilflingseder D, De Kock J, Vanhaecke T, Rogiers V, Jírová D, Kejlová K, Knudsen LE, Nielsen RN, Kleuser B, Kral V, Thöne-Reineke C, Hartung T, Pallocca G, Leist M, Hippenstiel S, Lang A, Retter I, Krämer S, Jedlicka P, Ameli K, Fritsche E, Tigges J, Buettner M, Bleich A, Baumgart N, Baumgart J, Meinhardt MW, Spanagel R, Chourbaji S, Kränzlin B, Seeger B, von Köckritz-Blickwede M, Sánchez-Morgado JM, Galligioni V, Ruiz-Pérez D, Movia D, Prina-Mello A, Ahluwalia A, Chiono V, Gutleb AC, Schmit M, van Golen B, van Weereld L, Kienhuis A, van Oort E, van der Valk J, Smith A, Roszak J, Stępnik M, Sobańska Z, Olsson IAS, Franco NH, Sevastre B, Kandarova H, Capdevila S, Johansson J, Cederroth CR, Sandström J, Ragan I, Bubalo N, Spielmann H. Neuhaus W, et al. Among authors: spielmann h. Altern Lab Anim. 2022 Mar;50(2):90-120. doi: 10.1177/02611929221099165. Epub 2022 May 16. Altern Lab Anim. 2022. PMID: 35578444
Assessment of the skin irritation potential of chemicals by using the SkinEthic reconstructed human epidermal model and the common skin irritation protocol evaluated in the ECVAM skin irritation validation study.
Kandárová H, Liebsch M, Schmidt E, Genschow E, Traue D, Spielmann H, Meyer K, Steinhoff C, Tornier C, De Wever B, Rosdy M. Kandárová H, et al. Among authors: spielmann h. Altern Lab Anim. 2006 Aug;34(4):393-406. doi: 10.1177/026119290603400407. Altern Lab Anim. 2006. PMID: 16945007
A proposed eye irritation testing strategy to reduce and replace in vivo studies using Bottom-Up and Top-Down approaches.
Scott L, Eskes C, Hoffmann S, Adriaens E, Alepée N, Bufo M, Clothier R, Facchini D, Faller C, Guest R, Harbell J, Hartung T, Kamp H, Varlet BL, Meloni M, McNamee P, Osborne R, Pape W, Pfannenbecker U, Prinsen M, Seaman C, Spielmann H, Stokes W, Trouba K, Berghe CV, Goethem FV, Vassallo M, Vinardell P, Zuang V. Scott L, et al. Among authors: spielmann h. Toxicol In Vitro. 2010 Feb;24(1):1-9. doi: 10.1016/j.tiv.2009.05.019. Epub 2009 May 31. Toxicol In Vitro. 2010. PMID: 19490935 Review.
A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment.
Scholz S, Sela E, Blaha L, Braunbeck T, Galay-Burgos M, García-Franco M, Guinea J, Klüver N, Schirmer K, Tanneberger K, Tobor-Kapłon M, Witters H, Belanger S, Benfenati E, Creton S, Cronin MT, Eggen RI, Embry M, Ekman D, Gourmelon A, Halder M, Hardy B, Hartung T, Hubesch B, Jungmann D, Lampi MA, Lee L, Léonard M, Küster E, Lillicrap A, Luckenbach T, Murk AJ, Navas JM, Peijnenburg W, Repetto G, Salinas E, Schüürmann G, Spielmann H, Tollefsen KE, Walter-Rohde S, Whale G, Wheeler JR, Winter MJ. Scholz S, et al. Among authors: spielmann h. Regul Toxicol Pharmacol. 2013 Dec;67(3):506-30. doi: 10.1016/j.yrtph.2013.10.003. Epub 2013 Oct 23. Regul Toxicol Pharmacol. 2013. PMID: 24161465 Review.
294 results