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Protocol for 3D screening of lung cancer spheroids using natural products.
Vega VF, Yang D, Jordán LO, Ye F, Conway L, Chen LY, Shumate J, Baillargeon P, Scampavia L, Parker C, Shen B, Spicer TP. Vega VF, et al. Among authors: spicer tp. SLAS Discov. 2023 Mar;28(2):20-28. doi: 10.1016/j.slasd.2023.01.005. Epub 2023 Jan 18. SLAS Discov. 2023. PMID: 36681384 Free PMC article.
Target-based screen against a periplasmic serine protease that regulates intrabacterial pH homeostasis in Mycobacterium tuberculosis.
Zhao N, Darby CM, Small J, Bachovchin DA, Jiang X, Burns-Huang KE, Botella H, Ehrt S, Boger DL, Anderson ED, Cravatt BF, Speers AE, Fernandez-Vega V, Hodder PS, Eberhart C, Rosen H, Spicer TP, Nathan CF. Zhao N, et al. Among authors: spicer tp. ACS Chem Biol. 2015 Feb 20;10(2):364-71. doi: 10.1021/cb500746z. Epub 2014 Dec 5. ACS Chem Biol. 2015. PMID: 25457457 Free PMC article.
Comparison of miniaturized time-resolved fluorescence resonance energy transfer and enzyme-coupled luciferase high-throughput screening assays to discover inhibitors of Rho-kinase II (ROCK-II).
Schröter T, Minond D, Weiser A, Dao C, Habel J, Spicer T, Chase P, Baillargeon P, Scampavia L, Schürer S, Chung C, Mader C, Southern M, Tsinoremas N, LoGrasso P, Hodder P. Schröter T, et al. J Biomol Screen. 2008 Jan;13(1):17-28. doi: 10.1177/1087057107310806. J Biomol Screen. 2008. PMID: 18227223
Identification of Potent and Selective Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PfM18AAP) of Human Malaria via High-Throughput Screening.
Spicer T, Fernandez-Vega V, Chase P, Scampavia L, To J, Dalton JP, Da Silva FL, Skinner-Adams TS, Gardiner DL, Trenholme KR, Brown CL, Ghosh P, Porubsky P, Wang JL, Whipple DA, Schoenen FJ, Hodder P. Spicer T, et al. J Biomol Screen. 2014 Aug;19(7):1107-15. doi: 10.1177/1087057114525852. Epub 2014 Mar 11. J Biomol Screen. 2014. PMID: 24619116 Free PMC article.
116 results