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Target-based discovery of a broad-spectrum flukicide.
Sprague DJ, Park SK, Gramberg S, Bauer L, Rohr CM, Chulkov EG, Smith E, Scampavia L, Spicer TP, Haeberlein S, Marchant JS. Sprague DJ, et al. Among authors: spicer tp. Nat Struct Mol Biol. 2024 May 7. doi: 10.1038/s41594-024-01298-3. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 38714890
Target-based discovery of a broad spectrum flukicide.
Sprague DJ, Park SK, Gramberg S, Bauer L, Rohr CM, Chulkov EG, Smith E, Scampavia L, Spicer TP, Haeberlein S, Marchant JS. Sprague DJ, et al. Among authors: spicer tp. bioRxiv [Preprint]. 2023 Sep 22:2023.09.22.559026. doi: 10.1101/2023.09.22.559026. bioRxiv. 2023. PMID: 37790347 Free PMC article. Preprint.
Neutral ceramidase-active site inhibitor chemotypes and binding modes.
Coant N, Bickel JD, Rahaim R, Otsuka Y, Choi YM, Xu R, Simoes M, Cariello C, Mao C, Saied EM, Arenz C, Spicer TP, Bannister TD, Tonge PJ, Airola MV, Scampavia L, Hannun YA, Rizzo RC, Haley JD. Coant N, et al. Among authors: spicer tp. Bioorg Chem. 2023 Oct;139:106747. doi: 10.1016/j.bioorg.2023.106747. Epub 2023 Jul 27. Bioorg Chem. 2023. PMID: 37531819 Free PMC article.
In Vitro and In Vivo Drug-Response Profiling Using Patient-Derived High-Grade Glioma.
Rajan RG, Fernandez-Vega V, Sperry J, Nakashima J, Do LH, Andrews W, Boca S, Islam R, Chowdhary SA, Seldin J, Souza GR, Scampavia L, Hanafy KA, Vrionis FD, Spicer TP. Rajan RG, et al. Among authors: spicer tp. Cancers (Basel). 2023 Jun 22;15(13):3289. doi: 10.3390/cancers15133289. Cancers (Basel). 2023. PMID: 37444398 Free PMC article.
191 results