Spicer J - Search Results

1

T-cell defects and postpartum depression.

Osborne LM, Gilden J, Kamperman AM, Hoogendijk WJG, Spicer J, Drexhage HA, Bergink V. Osborne LM, et al. Among authors: spicer j. Brain Behav Immun. 2020 Jul;87:397-403. doi: 10.1016/j.bbi.2020.01.007. Epub 2020 Jan 8. Brain Behav Immun. 2020. PMID: 31926288 Free PMC article.

2

IFN-γ⁺ cytotoxic CD4⁺ T lymphocytes are involved in the pathogenesis of colitis induced by IL-23 and the food colorant Red 40.

Chen L, He Z, Reis BS, Gelles JD, Chipuk JE, Ting AT, Spicer JA, Trapani JA, Furtado GC, Lira SA. Chen L, et al. Cell Mol Immunol. 2022 Jul;19(7):777-790. doi: 10.1038/s41423-022-00864-3. Epub 2022 Apr 25. Cell Mol Immunol. 2022. PMID: 35468944 Free PMC article.

3

Intergenerational Echoes of Climate Change.

Malaspina D, Howell EA, Spicer J. Malaspina D, et al. Among authors: spicer j. JAMA Psychiatry. 2020 Aug 1;77(8):778-780. doi: 10.1001/jamapsychiatry.2020.0604. JAMA Psychiatry. 2020. PMID: 32347914 No abstract available.

4

Dihydrofuro[3,4-c]pyridinones as inhibitors of the cytolytic effects of the pore-forming glycoprotein perforin.

Lena G, Trapani JA, Sutton VR, Ciccone A, Browne KA, Smyth MJ, Denny WA, Spicer JA. Lena G, et al. Among authors: spicer ja. J Med Chem. 2008 Dec 11;51(23):7614-24. doi: 10.1021/jm801063n. J Med Chem. 2008. PMID: 19007200

5

Inhibition of the cellular function of perforin by 1-amino-2,4-dicyanopyrido[1,2-a]benzimidazoles.

Lyons DM, Huttunen KM, Browne KA, Ciccone A, Trapani JA, Denny WA, Spicer JA. Lyons DM, et al. Bioorg Med Chem. 2011 Jul 1;19(13):4091-100. doi: 10.1016/j.bmc.2011.05.013. Epub 2011 May 18. Bioorg Med Chem. 2011. PMID: 21664824

6

Inhibition of the pore-forming protein perforin by a series of aryl-substituted isobenzofuran-1(3H)-ones.

Spicer JA, Huttunen KM, Miller CK, Denny WA, Ciccone A, Browne KA, Trapani JA. Spicer JA, et al. Bioorg Med Chem. 2012 Feb 1;20(3):1319-36. doi: 10.1016/j.bmc.2011.12.011. Epub 2011 Dec 22. Bioorg Med Chem. 2012. PMID: 22244072

7

Exploration of a series of 5-arylidene-2-thioxoimidazolidin-4-ones as inhibitors of the cytolytic protein perforin.

Spicer JA, Lena G, Lyons DM, Huttunen KM, Miller CK, O'Connor PD, Bull M, Helsby N, Jamieson SM, Denny WA, Ciccone A, Browne KA, Lopez JA, Rudd-Schmidt J, Voskoboinik I, Trapani JA. Spicer JA, et al. J Med Chem. 2013 Dec 12;56(23):9542-55. doi: 10.1021/jm401604x. Epub 2013 Nov 19. J Med Chem. 2013. PMID: 24195776 Free PMC article.

8

The preclinical pharmacokinetic disposition of a series of perforin-inhibitors as potential immunosuppressive agents.

Bull MR, Spicer JA, Huttunen KM, Denny WA, Ciccone A, Browne KA, Trapani JA, Helsby NA. Bull MR, et al. Among authors: spicer ja. Eur J Drug Metab Pharmacokinet. 2015 Dec;40(4):417-25. doi: 10.1007/s13318-014-0220-y. Epub 2014 Aug 26. Eur J Drug Metab Pharmacokinet. 2015. PMID: 25155444

9

Diarylthiophenes as inhibitors of the pore-forming protein perforin.

Miller CK, Huttunen KM, Denny WA, Jaiswal JK, Ciccone A, Browne KA, Trapani JA, Spicer JA. Miller CK, et al. Bioorg Med Chem Lett. 2016 Jan 15;26(2):355-360. doi: 10.1016/j.bmcl.2015.12.003. Epub 2015 Dec 7. Bioorg Med Chem Lett. 2016. PMID: 26711151 Free PMC article.

10

Benzenesulphonamide inhibitors of the cytolytic protein perforin.

Spicer JA, Miller CK, O'Connor PD, Jose J, Huttunen KM, Jaiswal JK, Denny WA, Akhlaghi H, Browne KA, Trapani JA. Spicer JA, et al. Bioorg Med Chem Lett. 2017 Feb 15;27(4):1050-1054. doi: 10.1016/j.bmcl.2016.12.057. Epub 2016 Dec 23. Bioorg Med Chem Lett. 2017. PMID: 28110869 Free PMC article.

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