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Synaptic Density and Neuronal Metabolic Function Measured by Positron Emission Tomography in the Unilateral 6-OHDA Rat Model of Parkinson's Disease.
Raval NR, Gudmundsen F, Juhl M, Andersen IV, Speth N, Videbæk A, Petersen IN, Mikkelsen JD, Fisher PM, Herth MM, Plavén-Sigray P, Knudsen GM, Palner M. Raval NR, et al. Among authors: speth n. Front Synaptic Neurosci. 2021 Nov 18;13:715811. doi: 10.3389/fnsyn.2021.715811. eCollection 2021. Front Synaptic Neurosci. 2021. PMID: 34867258 Free PMC article.
Blocking of efflux transporters in rats improves translational validation of brain radioligands.
Shalgunov V, Xiong M, L'Estrade ET, Raval NR, Andersen IV, Edgar FG, Speth NR, Baerentzen SL, Hansen HD, Donovan LL, Nasser A, Peitersen ST, Kjaer A, Knudsen GM, Syvänen S, Palner M, Herth MM. Shalgunov V, et al. Among authors: speth nr. EJNMMI Res. 2020 Oct 19;10(1):124. doi: 10.1186/s13550-020-00718-x. EJNMMI Res. 2020. PMID: 33074370 Free PMC article.
The selective 5-HT2A receptor agonist 25CN-NBOH: Structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [3H]25CN-NBOH.
Jensen AA, Halberstadt AL, Märcher-Rørsted E, Odland AU, Chatha M, Speth N, Liebscher G, Hansen M, Bräuner-Osborne H, Palner M, Andreasen JT, Kristensen JL. Jensen AA, et al. Among authors: speth n. Biochem Pharmacol. 2020 Jul;177:113979. doi: 10.1016/j.bcp.2020.113979. Epub 2020 Apr 13. Biochem Pharmacol. 2020. PMID: 32298690
Repeated low doses of psilocybin increase resilience to stress, lower compulsive actions, and strengthen cortical connections to the paraventricular thalamic nucleus in rats.
Kiilerich KF, Lorenz J, Scharff MB, Speth N, Brandt TG, Czurylo J, Xiong M, Jessen NS, Casado-Sainz A, Shalgunov V, Kjaerby C, Satała G, Bojarski AJ, Jensen AA, Herth MM, Cumming P, Overgaard A, Palner M. Kiilerich KF, et al. Among authors: speth n. Mol Psychiatry. 2023 Sep;28(9):3829-3841. doi: 10.1038/s41380-023-02280-z. Epub 2023 Oct 2. Mol Psychiatry. 2023. PMID: 37783788