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2-Mercaptomethyl Thiazolidines (MMTZs) Inhibit All Metallo-β-Lactamase Classes by Maintaining a Conserved Binding Mode.
Hinchliffe P, Moreno DM, Rossi MA, Mojica MF, Martinez V, Villamil V, Spellberg B, Drusano GL, Banchio C, Mahler G, Bonomo RA, Vila AJ, Spencer J. Hinchliffe P, et al. Among authors: spellberg b. ACS Infect Dis. 2021 Sep 10;7(9):2697-2706. doi: 10.1021/acsinfecdis.1c00194. Epub 2021 Aug 6. ACS Infect Dis. 2021. PMID: 34355567 Free PMC article.
Can Ceftazidime-Avibactam and Aztreonam Overcome β-Lactam Resistance Conferred by Metallo-β-Lactamases in Enterobacteriaceae?
Marshall S, Hujer AM, Rojas LJ, Papp-Wallace KM, Humphries RM, Spellberg B, Hujer KM, Marshall EK, Rudin SD, Perez F, Wilson BM, Wasserman RB, Chikowski L, Paterson DL, Vila AJ, van Duin D, Kreiswirth BN, Chambers HF, Fowler VG Jr, Jacobs MR, Pulse ME, Weiss WJ, Bonomo RA. Marshall S, et al. Among authors: spellberg b. Antimicrob Agents Chemother. 2017 Mar 24;61(4):e02243-16. doi: 10.1128/AAC.02243-16. Print 2017 Apr. Antimicrob Agents Chemother. 2017. PMID: 28167541 Free PMC article.
Klebsiella pneumoniae Carbapenemase-2 (KPC-2), Substitutions at Ambler Position Asp179, and Resistance to Ceftazidime-Avibactam: Unique Antibiotic-Resistant Phenotypes Emerge from β-Lactamase Protein Engineering.
Barnes MD, Winkler ML, Taracila MA, Page MG, Desarbre E, Kreiswirth BN, Shields RK, Nguyen MH, Clancy C, Spellberg B, Papp-Wallace KM, Bonomo RA. Barnes MD, et al. Among authors: spellberg b. mBio. 2017 Oct 31;8(5):e00528-17. doi: 10.1128/mBio.00528-17. mBio. 2017. PMID: 29089425 Free PMC article.
Natural history of Acinetobacter baumannii infection in mice.
Luna BM, Yan J, Reyna Z, Moon E, Nielsen TB, Reza H, Lu P, Bonomo R, Louie A, Drusano G, Bulitta J, She R, Spellberg B. Luna BM, et al. Among authors: spellberg b. PLoS One. 2019 Jul 18;14(7):e0219824. doi: 10.1371/journal.pone.0219824. eCollection 2019. PLoS One. 2019. PMID: 31318907 Free PMC article.
270 results