Spelbrink JN - Search Results

1

Replication factors transiently associate with mtDNA at the mitochondrial inner membrane to facilitate replication.

Rajala N, Gerhold JM, Martinsson P, Klymov A, Spelbrink JN. Rajala N, et al. Among authors: spelbrink jn. Nucleic Acids Res. 2014 Jan;42(2):952-67. doi: 10.1093/nar/gkt988. Epub 2013 Oct 25. Nucleic Acids Res. 2014. PMID: 24163258 Free PMC article.

2

Composition and dynamics of human mitochondrial nucleoids.

Garrido N, Griparic L, Jokitalo E, Wartiovaara J, van der Bliek AM, Spelbrink JN. Garrido N, et al. Among authors: spelbrink jn. Mol Biol Cell. 2003 Apr;14(4):1583-96. doi: 10.1091/mbc.e02-07-0399. Mol Biol Cell. 2003. PMID: 12686611 Free PMC article.

3

Twinkle and POLG defects enhance age-dependent accumulation of mutations in the control region of mtDNA.

Wanrooij S, Luoma P, van Goethem G, van Broeckhoven C, Suomalainen A, Spelbrink JN. Wanrooij S, et al. Among authors: spelbrink jn. Nucleic Acids Res. 2004 Jun 4;32(10):3053-64. doi: 10.1093/nar/gkh634. Print 2004. Nucleic Acids Res. 2004. PMID: 15181170 Free PMC article.

4

Alterations to the expression level of mitochondrial transcription factor A, TFAM, modify the mode of mitochondrial DNA replication in cultured human cells.

Pohjoismäki JL, Wanrooij S, Hyvärinen AK, Goffart S, Holt IJ, Spelbrink JN, Jacobs HT. Pohjoismäki JL, et al. Among authors: spelbrink jn. Nucleic Acids Res. 2006;34(20):5815-28. doi: 10.1093/nar/gkl703. Epub 2006 Oct 24. Nucleic Acids Res. 2006. PMID: 17062618 Free PMC article.

5

Expression of catalytic mutants of the mtDNA helicase Twinkle and polymerase POLG causes distinct replication stalling phenotypes.

Wanrooij S, Goffart S, Pohjoismäki JL, Yasukawa T, Spelbrink JN. Wanrooij S, et al. Among authors: spelbrink jn. Nucleic Acids Res. 2007;35(10):3238-51. doi: 10.1093/nar/gkm215. Epub 2007 Apr 22. Nucleic Acids Res. 2007. PMID: 17452351 Free PMC article.

6

Mammalian mitochondrial nucleoids: organizing an independently minded genome.

Holt IJ, He J, Mao CC, Boyd-Kirkup JD, Martinsson P, Sembongi H, Reyes A, Spelbrink JN. Holt IJ, et al. Among authors: spelbrink jn. Mitochondrion. 2007 Sep;7(5):311-21. doi: 10.1016/j.mito.2007.06.004. Epub 2007 Jul 4. Mitochondrion. 2007. PMID: 17698423 Review.

7

The mitochondrial transcription termination factor mTERF modulates replication pausing in human mitochondrial DNA.

Hyvärinen AK, Pohjoismäki JL, Reyes A, Wanrooij S, Yasukawa T, Karhunen PJ, Spelbrink JN, Holt IJ, Jacobs HT. Hyvärinen AK, et al. Among authors: spelbrink jn. Nucleic Acids Res. 2007;35(19):6458-74. doi: 10.1093/nar/gkm676. Epub 2007 Sep 20. Nucleic Acids Res. 2007. PMID: 17884915 Free PMC article.

8

The mitochondria of cultured mammalian cells: II. Expression and visualization of exogenous proteins in fixed and live cells.

Goffart S, Martinsson P, Malka F, Rojo M, Spelbrink JN. Goffart S, et al. Among authors: spelbrink jn. Methods Mol Biol. 2007;372:17-32. doi: 10.1007/978-1-59745-365-3_2. Methods Mol Biol. 2007. PMID: 18314715

9

Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling.

Goffart S, Cooper HM, Tyynismaa H, Wanrooij S, Suomalainen A, Spelbrink JN. Goffart S, et al. Among authors: spelbrink jn. Hum Mol Genet. 2009 Jan 15;18(2):328-40. doi: 10.1093/hmg/ddn359. Epub 2008 Oct 29. Hum Mol Genet. 2009. PMID: 18971204 Free PMC article.

10

Human Dna2 is a nuclear and mitochondrial DNA maintenance protein.

Duxin JP, Dao B, Martinsson P, Rajala N, Guittat L, Campbell JL, Spelbrink JN, Stewart SA. Duxin JP, et al. Among authors: spelbrink jn. Mol Cell Biol. 2009 Aug;29(15):4274-82. doi: 10.1128/MCB.01834-08. Epub 2009 Jun 1. Mol Cell Biol. 2009. PMID: 19487465 Free PMC article.

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