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Deletion of accessory genes 3a, 3b, 5a or 5b from avian coronavirus infectious bronchitis virus induces an attenuated phenotype both in vitro and in vivo.
J Gen Virol. 2018 Aug 1;99(10):1381-90. doi: 10.1099/jgv.0.001130. Online ahead of print.
J Gen Virol. 2018.
PMID: 30067172
Free PMC article.
A reverse genetics system for avian coronavirus infectious bronchitis virus based on targeted RNA recombination.
van Beurden SJ, Berends AJ, Krämer-Kühl A, Spekreijse D, Chénard G, Philipp HC, Mundt E, Rottier PJM, Verheije MH.
van Beurden SJ, et al. Among authors: spekreijse d.
Virol J. 2017 Jun 12;14(1):109. doi: 10.1186/s12985-017-0775-8.
Virol J. 2017.
PMID: 28606144
Free PMC article.
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Recombinant live attenuated avian coronavirus vaccines with deletions in the accessory genes 3ab and/or 5ab protect against infectious bronchitis in chickens.
van Beurden SJ, Berends AJ, Krämer-Kühl A, Spekreijse D, Chenard G, Philipp HC, Mundt E, Rottier PJM, Verheije MH.
van Beurden SJ, et al. Among authors: spekreijse d.
Vaccine. 2018 Feb 14;36(8):1085-1092. doi: 10.1016/j.vaccine.2018.01.017.
Vaccine. 2018.
PMID: 29366709
Free PMC article.
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Modelling the Innate Immune Response against Avian Influenza Virus in Chicken.
Hagenaars TJ, Fischer EA, Jansen CA, Rebel JM, Spekreijse D, Vervelde L, Backer JA, de Jong MC, Koets AP.
Hagenaars TJ, et al. Among authors: spekreijse d.
PLoS One. 2016 Jun 21;11(6):e0157816. doi: 10.1371/journal.pone.0157816. eCollection 2016.
PLoS One. 2016.
PMID: 27328069
Free PMC article.
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The effect of inoculation dose of a highly pathogenic avian influenza virus strain H5N1 on the infectiousness of chickens.
Spekreijse D, Bouma A, Stegeman JA, Koch G, de Jong MC.
Spekreijse D, et al.
Vet Microbiol. 2011 Jan 10;147(1-2):59-66. doi: 10.1016/j.vetmic.2010.06.012. Epub 2010 Jun 20.
Vet Microbiol. 2011.
PMID: 20619974
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Airborne transmission of a highly pathogenic avian influenza virus strain H5N1 between groups of chickens quantified in an experimental setting.
Spekreijse D, Bouma A, Koch G, Stegeman JA.
Spekreijse D, et al.
Vet Microbiol. 2011 Aug 26;152(1-2):88-95. doi: 10.1016/j.vetmic.2011.04.024. Epub 2011 Apr 22.
Vet Microbiol. 2011.
PMID: 21565455
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Quantification of dust-borne transmission of highly pathogenic avian influenza virus between chickens.
Spekreijse D, Bouma A, Koch G, Stegeman A.
Spekreijse D, et al.
Influenza Other Respir Viruses. 2013 Mar;7(2):132-8. doi: 10.1111/j.1750-2659.2012.00362.x. Epub 2012 Apr 6.
Influenza Other Respir Viruses. 2013.
PMID: 22487257
Free PMC article.
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