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Reduction of use of animals in regulatory genotoxicity testing: Identification and implementation opportunities-Report from an ECVAM workshop.
Pfuhler S, Kirkland D, Kasper P, Hayashi M, Vanparys P, Carmichael P, Dertinger S, Eastmond D, Elhajouji A, Krul C, Rothfuss A, Schoening G, Smith A, Speit G, Thomas C, van Benthem J, Corvi R. Pfuhler S, et al. Among authors: speit g. Mutat Res. 2009 Nov-Dec;680(1-2):31-42. doi: 10.1016/j.mrgentox.2009.09.002. Epub 2009 Sep 16. Mutat Res. 2009. PMID: 19765670
Dysfunction of the MDM2/p53 axis is linked to premature aging.
Lessel D, Wu D, Trujillo C, Ramezani T, Lessel I, Alwasiyah MK, Saha B, Hisama FM, Rading K, Goebel I, Schütz P, Speit G, Högel J, Thiele H, Nürnberg G, Nürnberg P, Hammerschmidt M, Zhu Y, Tong DR, Katz C, Martin GM, Oshima J, Prives C, Kubisch C. Lessel D, et al. Among authors: speit g. J Clin Invest. 2017 Oct 2;127(10):3598-3608. doi: 10.1172/JCI92171. Epub 2017 Aug 28. J Clin Invest. 2017. PMID: 28846075 Free PMC article.
DNA Damage-Induced HSPC Malfunction Depends on ROS Accumulation Downstream of IFN-1 Signaling and Bid Mobilization.
Tasdogan A, Kumar S, Allies G, Bausinger J, Beckel F, Hofemeister H, Mulaw M, Madan V, Scharffetter-Kochanek K, Feuring-Buske M, Doehner K, Speit G, Stewart AF, Fehling HJ. Tasdogan A, et al. Among authors: speit g. Cell Stem Cell. 2017 Mar 2;20(3):415. doi: 10.1016/j.stem.2017.02.002. Cell Stem Cell. 2017. PMID: 28257711 Free article. No abstract available.
FUS Mislocalization and Vulnerability to DNA Damage in ALS Patients Derived hiPSCs and Aging Motoneurons.
Higelin J, Demestre M, Putz S, Delling JP, Jacob C, Lutz AK, Bausinger J, Huber AK, Klingenstein M, Barbi G, Speit G, Huebers A, Weishaupt JH, Hermann A, Liebau S, Ludolph AC, Boeckers TM. Higelin J, et al. Among authors: speit g. Front Cell Neurosci. 2016 Dec 26;10:290. doi: 10.3389/fncel.2016.00290. eCollection 2016. Front Cell Neurosci. 2016. PMID: 28082870 Free PMC article.
DNA Damage-Induced HSPC Malfunction Depends on ROS Accumulation Downstream of IFN-1 Signaling and Bid Mobilization.
Tasdogan A, Kumar S, Allies G, Bausinger J, Beckel F, Hofemeister H, Mulaw M, Madan V, Scharffetter-Kochanek K, Feuring-Buske M, Doehner K, Speit G, Stewart AF, Fehling HJ. Tasdogan A, et al. Among authors: speit g. Cell Stem Cell. 2016 Dec 1;19(6):752-767. doi: 10.1016/j.stem.2016.08.007. Epub 2016 Sep 15. Cell Stem Cell. 2016. PMID: 27641306 Free article.
195 results