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CD4+ T cells in cancer.
Speiser DE, Chijioke O, Schaeuble K, Münz C. Speiser DE, et al. Nat Cancer. 2023 Mar;4(3):317-329. doi: 10.1038/s43018-023-00521-2. Epub 2023 Mar 9. Nat Cancer. 2023. PMID: 36894637 Review.
Tumor antigen-specific FOXP3+ CD4 T cells identified in human metastatic melanoma: peptide vaccination results in selective expansion of Th1-like counterparts.
Jandus C, Bioley G, Dojcinovic D, Derré L, Baitsch L, Wieckowski S, Rufer N, Kwok WW, Tiercy JM, Luescher IF, Speiser DE, Romero P. Jandus C, et al. Among authors: speiser de. Cancer Res. 2009 Oct 15;69(20):8085-93. doi: 10.1158/0008-5472.CAN-09-2226. Epub 2009 Oct 6. Cancer Res. 2009. PMID: 19808957 Free article.
Vaccination with LAG-3Ig (IMP321) and Peptides Induces Specific CD4 and CD8 T-Cell Responses in Metastatic Melanoma Patients--Report of a Phase I/IIa Clinical Trial.
Legat A, Maby-El Hajjami H, Baumgaertner P, Cagnon L, Abed Maillard S, Geldhof C, Iancu EM, Lebon L, Guillaume P, Dojcinovic D, Michielin O, Romano E, Berthod G, Rimoldi D, Triebel F, Luescher I, Rufer N, Speiser DE. Legat A, et al. Among authors: speiser de. Clin Cancer Res. 2016 Mar 15;22(6):1330-40. doi: 10.1158/1078-0432.CCR-15-1212. Epub 2015 Oct 23. Clin Cancer Res. 2016. PMID: 26500235 Free article. Clinical Trial.
Broad and Conserved Immune Regulation by Genetically Heterogeneous Melanoma Cells.
Neubert NJ, Tillé L, Barras D, Soneson C, Baumgaertner P, Rimoldi D, Gfeller D, Delorenzi M, Fuertes Marraco SA, Speiser DE. Neubert NJ, et al. Among authors: speiser de. Cancer Res. 2017 Apr 1;77(7):1623-1636. doi: 10.1158/0008-5472.CAN-16-2680. Epub 2017 Jan 19. Cancer Res. 2017. PMID: 28104684
Lymphatic vessel density is associated with CD8+ T cell infiltration and immunosuppressive factors in human melanoma.
Bordry N, Broggi MAS, de Jonge K, Schaeuble K, Gannon PO, Foukas PG, Danenberg E, Romano E, Baumgaertner P, Fankhauser M, Wald N, Cagnon L, Abed-Maillard S, Maby-El Hajjami H, Murray T, Ioannidou K, Letovanec I, Yan P, Michielin O, Matter M, Swartz MA, Speiser DE. Bordry N, et al. Among authors: de jonge k, speiser de. Oncoimmunology. 2018 May 31;7(8):e1462878. doi: 10.1080/2162402X.2018.1462878. eCollection 2018. Oncoimmunology. 2018. PMID: 30221058 Free PMC article.
Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy.
Siddiqui I, Schaeuble K, Chennupati V, Fuertes Marraco SA, Calderon-Copete S, Pais Ferreira D, Carmona SJ, Scarpellino L, Gfeller D, Pradervand S, Luther SA, Speiser DE, Held W. Siddiqui I, et al. Among authors: speiser de. Immunity. 2019 Jan 15;50(1):195-211.e10. doi: 10.1016/j.immuni.2018.12.021. Epub 2019 Jan 8. Immunity. 2019. PMID: 30635237 Free article.
High-throughput Screening of Human Tumor Antigen-specific CD4 T Cells, Including Neoantigen-reactive T Cells.
Costa-Nunes C, Cachot A, Bobisse S, Arnaud M, Genolet R, Baumgaertner P, Speiser DE, Sousa Alves PM, Sandoval F, Adotévi O, Reith W, Protti MP, Coukos G, Harari A, Romero P, Jandus C. Costa-Nunes C, et al. Among authors: speiser de. Clin Cancer Res. 2019 Jul 15;25(14):4320-4331. doi: 10.1158/1078-0432.CCR-18-1356. Epub 2019 Apr 23. Clin Cancer Res. 2019. PMID: 31015344
294 results