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Page 1
CD8+ CD226high T cells in liver metastases dictate the prognosis of colorectal cancer patients treated with chemotherapy and radical surgery.
Viot J, Abdeljaoued S, Vienot A, Seffar E, Spehner L, Bouard A, Asgarov K, Pallandre JR, Renaude E, Klajer E, Molimard C, Monnien F, Bibeau F, Turco C, Heyd B, Peixoto P, Hervouet E, Loyon R, Doussot A, Borg C, Kroemer M. Viot J, et al. Among authors: spehner l. Cell Mol Immunol. 2023 Apr;20(4):365-378. doi: 10.1038/s41423-023-00978-2. Epub 2023 Jan 30. Cell Mol Immunol. 2023. PMID: 36717657 Free PMC article.
SALL4 oncogene is an immunogenic antigen presented in various HLA-DR contexts.
Kroemer M, Spehner L, Mercier-Letondal P, Boullerot L, Kim S, Jary M, Galaine J, Picard E, Ferrand C, Nguyen T, Larosa F, Adotévi O, Godet Y, Borg C. Kroemer M, et al. Among authors: spehner l. Oncoimmunology. 2018 Jan 17;7(4):e1412030. doi: 10.1080/2162402X.2017.1412030. eCollection 2018. Oncoimmunology. 2018. PMID: 29632725 Free PMC article.
Circulating NKp46+ Natural Killer cells have a potential regulatory property and predict distinct survival in Non-Small Cell Lung Cancer.
Picard E, Godet Y, Laheurte C, Dosset M, Galaine J, Beziaud L, Loyon R, Boullerot L, Lauret Marie Joseph E, Spehner L, Jacquin M, Eberst G, Gaugler B, Le Pimpec-Barthes F, Fabre E, Westeel V, Caignard A, Borg C, Adotévi O. Picard E, et al. Among authors: spehner l. Oncoimmunology. 2018 Oct 19;8(2):e1527498. doi: 10.1080/2162402X.2018.1527498. eCollection 2019. Oncoimmunology. 2018. PMID: 30713781 Free PMC article.
COVID-19 patients display distinct SARS-CoV-2 specific T-cell responses according to disease severity.
Kroemer M, Spehner L, Vettoretti L, Bouard A, Eberst G, Pili Floury S, Capellier G, Lepiller Q, Orillard E, Mansi L, Clairet AL, Westeel V, Limat S, Dubois M, Malinowski L, Bohard L, Borg C, Chirouze C, Bouiller K. Kroemer M, et al. Among authors: spehner l. J Infect. 2021 Feb;82(2):282-327. doi: 10.1016/j.jinf.2020.08.036. Epub 2020 Aug 25. J Infect. 2021. PMID: 32853599 Free PMC article.
Anti-Telomerase CD4+ Th1 Immunity and Monocytic-Myeloid-Derived-Suppressor Cells Are Associated with Long-Term Efficacy Achieved by Docetaxel, Cisplatin, and 5-Fluorouracil (DCF) in Advanced Anal Squamous Cell Carcinoma: Translational Study of Epitopes-HPV01 and 02 Trials.
Spehner L, Kim S, Vienot A, François E, Buecher B, Adotevi O, Vernerey D, Abdeljaoued S, Meurisse A, Borg C. Spehner L, et al. Int J Mol Sci. 2020 Sep 17;21(18):6838. doi: 10.3390/ijms21186838. Int J Mol Sci. 2020. PMID: 32957741 Free PMC article. Clinical Trial.
Investigation of the prognostic value of CD4 T cell subsets expanded from tumor-infiltrating lymphocytes of colorectal cancer liver metastases.
Kroemer M, Turco C, Spehner L, Viot J, Idirène I, Bouard A, Renaude E, Deschamps M, Godet Y, Adotévi O, Limat S, Heyd B, Jary M, Loyon R, Borg C. Kroemer M, et al. Among authors: spehner l. J Immunother Cancer. 2020 Nov;8(2):e001478. doi: 10.1136/jitc-2020-001478. J Immunother Cancer. 2020. PMID: 33229508 Free PMC article.
[Squamous cell anal carcinoma. What's next ?].
Kim S, Spehner L, Cabel L, Bidard FC, Borg C. Kim S, et al. Among authors: spehner l. Bull Cancer. 2021 Jan;108(1):80-89. doi: 10.1016/j.bulcan.2020.12.001. Epub 2021 Jan 8. Bull Cancer. 2021. PMID: 33423780 Review. French.
Study of the SARS-CoV-2-specific immune T-cell responses in COVID-19-positive cancer patients.
Mansi L, Spehner L, Daguindau E, Bouiller K, Almotlak H, Stein U, Bouard A, Kim S, Klajer E, Jary M, Meynard G, Vienot A, Nardin C, Bazan F, Lepiller Q, Westeel V, Adotévi O, Borg C, Kroemer M. Mansi L, et al. Among authors: spehner l. Eur J Cancer. 2021 Jun;150:1-9. doi: 10.1016/j.ejca.2021.03.033. Epub 2021 Mar 26. Eur J Cancer. 2021. PMID: 33882374 Free PMC article. Clinical Trial.
Chemoradiation triggers antitumor Th1 and tissue resident memory-polarized immune responses to improve immune checkpoint inhibitors therapy.
Lauret Marie Joseph E, Kirilovsky A, Lecoester B, El Sissy C, Boullerot L, Rangan L, Marguier A, Tochet F, Dosset M, Boustani J, Ravel P, Boidot R, Spehner L, Haicheur-Adjouri N, Marliot F, Pallandre JR, Bonnefoy F, Scripcariu V, Van den Eynde M, Cornillot E, Mirjolet C, Pages F, Adotevi O. Lauret Marie Joseph E, et al. Among authors: spehner l. J Immunother Cancer. 2021 Jul;9(7):e002256. doi: 10.1136/jitc-2020-002256. J Immunother Cancer. 2021. PMID: 34230108 Free PMC article.
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