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253 results

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Early immune pressure initiated by tissue-resident memory T cells sculpts tumor evolution in non-small cell lung cancer.
Weeden CE, Gayevskiy V, Marceaux C, Batey D, Tan T, Yokote K, Ribera NT, Clatch A, Christo S, Teh CE, Mitchell AJ, Trussart M, Rankin L, Obers A, McDonald JA, Sutherland KD, Sharma VJ, Starkey G, D'Costa R, Antippa P, Leong T, Steinfort D, Irving L, Swanton C, Gordon CL, Mackay LK, Speed TP, Gray DHD, Asselin-Labat ML. Weeden CE, et al. Among authors: speed tp. Cancer Cell. 2023 May 8;41(5):837-852.e6. doi: 10.1016/j.ccell.2023.03.019. Epub 2023 Apr 21. Cancer Cell. 2023. PMID: 37086716 Free article.
Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer.
Virassamy B, Caramia F, Savas P, Sant S, Wang J, Christo SN, Byrne A, Clarke K, Brown E, Teo ZL, von Scheidt B, Freestone D, Gandolfo LC, Weber K, Teply-Szymanski J, Li R, Luen SJ, Denkert C, Loibl S, Lucas O, Swanton C, Speed TP, Darcy PK, Neeson PJ, Mackay LK, Loi S. Virassamy B, et al. Among authors: speed tp. Cancer Cell. 2023 Mar 13;41(3):585-601.e8. doi: 10.1016/j.ccell.2023.01.004. Epub 2023 Feb 23. Cancer Cell. 2023. PMID: 36827978 Free article.
Stem cell plasticity, acetylation of H3K14, and de novo gene activation rely on KAT7.
Kueh AJ, Bergamasco MI, Quaglieri A, Phipson B, Li-Wai-Suen CSN, Lönnstedt IM, Hu Y, Feng ZP, Woodruff C, May RE, Wilcox S, Garnham AL, Snyder MP, Smyth GK, Speed TP, Thomas T, Voss AK. Kueh AJ, et al. Among authors: speed tp. Cell Rep. 2023 Jan 31;42(1):111980. doi: 10.1016/j.celrep.2022.111980. Epub 2023 Jan 14. Cell Rep. 2023. PMID: 36641753 Free article.
Genomic characterisation of hormone receptor-positive breast cancer arising in very young women.
Luen SJ, Viale G, Nik-Zainal S, Savas P, Kammler R, Dell'Orto P, Biasi O, Degasperi A, Brown LC, Láng I, MacGrogan G, Tondini C, Bellet M, Villa F, Bernardo A, Ciruelos E, Karlsson P, Neven P, Climent M, Müller B, Jochum W, Bonnefoi H, Martino S, Davidson NE, Geyer C, Chia SK, Ingle JN, Coleman R, Solbach C, Thürlimann B, Colleoni M, Coates AS, Goldhirsch A, Fleming GF, Francis PA, Speed TP, Regan MM, Loi S. Luen SJ, et al. Among authors: speed tp. Ann Oncol. 2023 Apr;34(4):397-409. doi: 10.1016/j.annonc.2023.01.009. Epub 2023 Jan 25. Ann Oncol. 2023. PMID: 36709040 Free PMC article.
Divergent molecular networks program functionally distinct CD8+ skin-resident memory T cells.
Park SL, Christo SN, Wells AC, Gandolfo LC, Zaid A, Alexandre YO, Burn TN, Schröder J, Collins N, Han SJ, Guillaume SM, Evrard M, Castellucci C, Davies B, Osman M, Obers A, McDonald KM, Wang H, Mueller SN, Kannourakis G, Berzins SP, Mielke LA, Carbone FR, Kallies A, Speed TP, Belkaid Y, Mackay LK. Park SL, et al. Among authors: speed tp. Science. 2023 Dec;382(6674):1073-1079. doi: 10.1126/science.adi8885. Epub 2023 Nov 30. Science. 2023. PMID: 38033053
sccomp: Robust differential composition and variability analysis for single-cell data.
Mangiola S, Roth-Schulze AJ, Trussart M, Zozaya-Valdés E, Ma M, Gao Z, Rubin AF, Speed TP, Shim H, Papenfuss AT. Mangiola S, et al. Among authors: speed tp. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2203828120. doi: 10.1073/pnas.2203828120. Epub 2023 Aug 7. Proc Natl Acad Sci U S A. 2023. PMID: 37549298 Free PMC article.
Spatial analysis with SPIAT and spaSim to characterize and simulate tissue microenvironments.
Feng Y, Yang T, Zhu J, Li M, Doyle M, Ozcoban V, Bass GT, Pizzolla A, Cain L, Weng S, Pasam A, Kocovski N, Huang YK, Keam SP, Speed TP, Neeson PJ, Pearson RB, Sandhu S, Goode DL, Trigos AS. Feng Y, et al. Among authors: speed tp. Nat Commun. 2023 May 15;14(1):2697. doi: 10.1038/s41467-023-37822-0. Nat Commun. 2023. PMID: 37188662 Free PMC article.
An open protocol for modeling T Cell Clonotype repertoires using TCRβ CDR3 sequences.
Gurun B, Horton W, Murugan D, Zhu B, Leyshock P, Kumar S, Byrne KT, Vonderheide RH, Margolin AA, Mori M, Spellman PT, Coussens LM, Speed TP. Gurun B, et al. Among authors: speed tp. Res Sq [Preprint]. 2023 Feb 16:rs.3.rs-2140339. doi: 10.21203/rs.3.rs-2140339/v1. Res Sq. 2023. PMID: 36824803 Free PMC article. Updated. Preprint.
253 results