Speck C - Search Results

1

Evolution of an Amniote-Specific Mechanism for Modulating Ubiquitin Signaling via Phosphoregulation of the E2 Enzyme UBE2D3.

Roman-Trufero M, Ito CM, Pedebos C, Magdalou I, Wang YF, Karimi MM, Moyon B, Webster Z, di Gregorio A, Azuara V, Khalid S, Speck C, Rodriguez T, Dillon N. Roman-Trufero M, et al. Among authors: speck c. Mol Biol Evol. 2020 Jul 1;37(7):1986-2001. doi: 10.1093/molbev/msaa060. Mol Biol Evol. 2020. PMID: 32145025 Free PMC article.

2

Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.

Yuan Z, Schneider S, Dodd T, Riera A, Bai L, Yan C, Magdalou I, Ivanov I, Stillman B, Li H, Speck C. Yuan Z, et al. Among authors: speck c. Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):17747-17756. doi: 10.1073/pnas.2006231117. Epub 2020 Jul 15. Proc Natl Acad Sci U S A. 2020. PMID: 32669428 Free PMC article.

3

An ORC/Cdc6/MCM2-7 complex is formed in a multistep reaction to serve as a platform for MCM double-hexamer assembly.

Fernández-Cid A, Riera A, Tognetti S, Herrera MC, Samel S, Evrin C, Winkler C, Gardenal E, Uhle S, Speck C. Fernández-Cid A, et al. Among authors: speck c. Mol Cell. 2013 May 23;50(4):577-88. doi: 10.1016/j.molcel.2013.03.026. Epub 2013 Apr 18. Mol Cell. 2013. PMID: 23603117 Free article.

4

An integrated workflow for crosslinking mass spectrometry.

Mendes ML, Fischer L, Chen ZA, Barbon M, O'Reilly FJ, Giese SH, Bohlke-Schneider M, Belsom A, Dau T, Combe CW, Graham M, Eisele MR, Baumeister W, Speck C, Rappsilber J. Mendes ML, et al. Among authors: speck c. Mol Syst Biol. 2019 Sep;15(9):e8994. doi: 10.15252/msb.20198994. Mol Syst Biol. 2019. PMID: 31556486 Free PMC article.

5

From structure to mechanism-understanding initiation of DNA replication.

Riera A, Barbon M, Noguchi Y, Reuter LM, Schneider S, Speck C. Riera A, et al. Among authors: speck c. Genes Dev. 2017 Jun 1;31(11):1073-1088. doi: 10.1101/gad.298232.117. Genes Dev. 2017. PMID: 28717046 Free PMC article. Review.

6

Replicating repetitive DNA.

Tognetti S, Speck C. Tognetti S, et al. Among authors: speck c. Nat Cell Biol. 2016 May 27;18(6):593-4. doi: 10.1038/ncb3367. Nat Cell Biol. 2016. PMID: 27230530 Free article.

7

Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1.

Yuan Z, Riera A, Bai L, Sun J, Nandi S, Spanos C, Chen ZA, Barbon M, Rappsilber J, Stillman B, Speck C, Li H. Yuan Z, et al. Among authors: speck c. Nat Struct Mol Biol. 2017 Mar;24(3):316-324. doi: 10.1038/nsmb.3372. Epub 2017 Feb 13. Nat Struct Mol Biol. 2017. PMID: 28191893 Free PMC article.

8

In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2-7 hexamer dimerization.

Evrin C, Fernández-Cid A, Zech J, Herrera MC, Riera A, Clarke P, Brill S, Lurz R, Speck C. Evrin C, et al. Among authors: speck c. Nucleic Acids Res. 2013 Mar 1;41(5):3162-72. doi: 10.1093/nar/gkt043. Epub 2013 Feb 1. Nucleic Acids Res. 2013. PMID: 23376927 Free PMC article.

9

The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formation.

Evrin C, Fernández-Cid A, Riera A, Zech J, Clarke P, Herrera MC, Tognetti S, Lurz R, Speck C. Evrin C, et al. Among authors: speck c. Nucleic Acids Res. 2014 Feb;42(4):2257-69. doi: 10.1093/nar/gkt1148. Epub 2013 Nov 14. Nucleic Acids Res. 2014. PMID: 24234446 Free PMC article.

10

The fidelity of synaptonemal complex assembly is regulated by a signaling mechanism that controls early meiotic progression.

Silva N, Ferrandiz N, Barroso C, Tognetti S, Lightfoot J, Telecan O, Encheva V, Faull P, Hanni S, Furger A, Snijders AP, Speck C, Martinez-Perez E. Silva N, et al. Among authors: speck c. Dev Cell. 2014 Nov 24;31(4):503-11. doi: 10.1016/j.devcel.2014.10.001. Epub 2014 Nov 6. Dev Cell. 2014. PMID: 25455309 Free article.

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