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De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
Kessler MD, Loesch DP, Perry JA, Heard-Costa NL, Taliun D, Cade BE, Wang H, Daya M, Ziniti J, Datta S, Celedón JC, Soto-Quiros ME, Avila L, Weiss ST, Barnes K, Redline SS, Vasan RS, Johnson AD, Mathias RA, Hernandez R, Wilson JG, Nickerson DA, Abecasis G, Browning SR, Zöllner S, O'Connell JR, Mitchell BD; National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium; TOPMed Population Genetics Working Group; O'Connor TD. Kessler MD, et al. Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2560-2569. doi: 10.1073/pnas.1902766117. Epub 2020 Jan 21. Proc Natl Acad Sci U S A. 2020. PMID: 31964835 Free PMC article.
The Effects of Migration and Assortative Mating on Admixture Linkage Disequilibrium.
Zaitlen N, Huntsman S, Hu D, Spear M, Eng C, Oh SS, White MJ, Mak A, Davis A, Meade K, Brigino-Buenaventura E, LeNoir MA, Bibbins-Domingo K, Burchard EG, Halperin E. Zaitlen N, et al. Among authors: spear m. Genetics. 2017 Jan;205(1):375-383. doi: 10.1534/genetics.116.192138. Epub 2016 Nov 22. Genetics. 2017. PMID: 27879348 Free PMC article.
Reduction of large vessel traffic improves water quality and alters fish habitat-use throughout a large river.
Spear MJ, Harris BS, Bookout TA, Ickes BS, Jankowski KJ, Solomon LE, Maxson KA, Whitten AL, Mathis AT, Schaick SJ, Williams JA, DeBoer JA, Lenaerts AW, Hine EC, Chick JH, Lamer JT. Spear MJ, et al. Sci Total Environ. 2024 Apr 24:172705. doi: 10.1016/j.scitotenv.2024.172705. Online ahead of print. Sci Total Environ. 2024. PMID: 38670381 Free article.
CT109-SN-38, a Novel Antibody-drug Conjugate with Dual Specificity for CEACAM5 and 6, Elicits Potent Killing of Pancreatic Cancer Cells.
Arias Cardenas KC, Enos CW, Spear MR, Austin DE, Almofeez R, Kortchak S, Pincus L, Guo HB, Dolezal S, Pierce JM, Furth E, Gineste C, Kwon Y, Gelber C. Arias Cardenas KC, et al. Among authors: spear mr. Curr Cancer Drug Targets. 2024 Jan 4. doi: 10.2174/0115680096260614231115192343. Online ahead of print. Curr Cancer Drug Targets. 2024. PMID: 38178674
177 results