Spear KL - Search Results

1

Video-based Parkinson's disease assessments in a nationwide cohort of Fox Insight participants.

Myers TL, Tarolli CG, Adams JL, Barbano R, Cristina Gil-Díaz M, Spear KL, Lowell J, Daeschler M, Riley L, Amondikar N, Auinger P, Marras C, Tanner CM, Ray Dorsey E, Schneider RB. Myers TL, et al. Among authors: spear kl. Clin Park Relat Disord. 2021 May 24;4:100094. doi: 10.1016/j.prdoa.2021.100094. eCollection 2021. Clin Park Relat Disord. 2021. PMID: 34316671 Free PMC article.

2

Telemedicine: A valuable tool in neurodegenerative diseases.

Adams JL, Myers TL, Waddell EM, Spear KL, Schneider RB. Adams JL, et al. Among authors: spear kl. Curr Geriatr Rep. 2020 Jun;9(2):72-81. doi: 10.1007/s13670-020-00311-z. Epub 2020 Mar 14. Curr Geriatr Rep. 2020. PMID: 32509504 Free PMC article.

3

Using Smartphones and Machine Learning to Quantify Parkinson Disease Severity: The Mobile Parkinson Disease Score.

Zhan A, Mohan S, Tarolli C, Schneider RB, Adams JL, Sharma S, Elson MJ, Spear KL, Glidden AM, Little MA, Terzis A, Dorsey ER, Saria S. Zhan A, et al. Among authors: spear kl. JAMA Neurol. 2018 Jul 1;75(7):876-880. doi: 10.1001/jamaneurol.2018.0809. JAMA Neurol. 2018. PMID: 29582075 Free PMC article.

4

GEORGE®: A Pilot Study of a Smartphone Application for Huntington's Disease.

Waddell EM, Dinesh K, Spear KL, Elson MJ, Wagner E, Curtis MJ, Mitten DJ, Tarolli CG, Sharma G, Dorsey ER, Adams JL. Waddell EM, et al. Among authors: spear kl. J Huntingtons Dis. 2021;10(2):293-301. doi: 10.3233/JHD-200452. J Huntingtons Dis. 2021. PMID: 33814455

5

Patient Views on Telemedicine for Parkinson Disease.

Spear KL, Auinger P, Simone R, Dorsey ER, Francis J. Spear KL, et al. J Parkinsons Dis. 2019;9(2):401-404. doi: 10.3233/JPD-181557. J Parkinsons Dis. 2019. PMID: 31127732

6

SEP-363856, a Novel Psychotropic Agent with a Unique, Non-D₂ Receptor Mechanism of Action.

Dedic N, Jones PG, Hopkins SC, Lew R, Shao L, Campbell JE, Spear KL, Large TH, Campbell UC, Hanania T, Leahy E, Koblan KS. Dedic N, et al. Among authors: spear kl. J Pharmacol Exp Ther. 2019 Oct;371(1):1-14. doi: 10.1124/jpet.119.260281. Epub 2019 Aug 1. J Pharmacol Exp Ther. 2019. PMID: 31371483

7

The evolution of library design: crafting smart compound collections for phenotypic screens.

Spear KL, Brown SP. Spear KL, et al. Drug Discov Today Technol. 2017 Mar;23:61-67. doi: 10.1016/j.ddtec.2017.05.001. Epub 2017 May 30. Drug Discov Today Technol. 2017. PMID: 28647087 Review.

8

Novel human D-amino acid oxidase inhibitors stabilize an active-site lid-open conformation.

Terry-Lorenzo RT, Chun LE, Brown SP, Heffernan ML, Fang QK, Orsini MA, Pollegioni L, Hardy LW, Spear KL, Large TH. Terry-Lorenzo RT, et al. Among authors: spear kl. Biosci Rep. 2014 Aug 11;34(4):e00133. doi: 10.1042/BSR20140071. Biosci Rep. 2014. PMID: 25001371 Free PMC article.

9

Effects of D-amino acid oxidase inhibition on memory performance and long-term potentiation in vivo.

Hopkins SC, Campbell UC, Heffernan ML, Spear KL, Jeggo RD, Spanswick DC, Varney MA, Large TH. Hopkins SC, et al. Among authors: spear kl. Pharmacol Res Perspect. 2013 Oct;1(1):e00007. doi: 10.1002/prp2.7. Epub 2013 Oct 1. Pharmacol Res Perspect. 2013. PMID: 25505561 Free PMC article.

10

Structural, kinetic, and pharmacodynamic mechanisms of D-amino acid oxidase inhibition by small molecules.

Hopkins SC, Heffernan ML, Saraswat LD, Bowen CA, Melnick L, Hardy LW, Orsini MA, Allen MS, Koch P, Spear KL, Foglesong RJ, Soukri M, Chytil M, Fang QK, Jones SW, Varney MA, Panatier A, Oliet SH, Pollegioni L, Piubelli L, Molla G, Nardini M, Large TH. Hopkins SC, et al. Among authors: spear kl. J Med Chem. 2013 May 9;56(9):3710-24. doi: 10.1021/jm4002583. Epub 2013 Apr 30. J Med Chem. 2013. PMID: 23631755

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