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The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice.
Castoldi M, Vujic Spasic M, Altamura S, Elmén J, Lindow M, Kiss J, Stolte J, Sparla R, D'Alessandro LA, Klingmüller U, Fleming RE, Longerich T, Gröne HJ, Benes V, Kauppinen S, Hentze MW, Muckenthaler MU. Castoldi M, et al. Among authors: sparla r. J Clin Invest. 2011 Apr;121(4):1386-96. doi: 10.1172/JCI44883. J Clin Invest. 2011. PMID: 21364282 Free PMC article.
Smad6 and Smad7 are co-regulated with hepcidin in mouse models of iron overload.
Vujić Spasić M, Sparla R, Mleczko-Sanecka K, Migas MC, Breitkopf-Heinlein K, Dooley S, Vaulont S, Fleming RE, Muckenthaler MU. Vujić Spasić M, et al. Among authors: sparla r. Biochim Biophys Acta. 2013 Jan;1832(1):76-84. doi: 10.1016/j.bbadis.2012.08.013. Epub 2012 Aug 31. Biochim Biophys Acta. 2013. PMID: 22960056 Free PMC article.
Cell-specific expression of Hfe determines the outcome of Salmonella enterica serovar Typhimurium infection in mice.
Nairz M, Metzendorf C, Vujic-Spasic M, Mitterstiller AM, Schroll A, Haschka D, Hoffmann A, Von Raffay L, Sparla R, Huck CW, Talasz H, Moser PL, Muckenthaler MU, Weiss G. Nairz M, et al. Among authors: sparla r. Haematologica. 2021 Dec 1;106(12):3149-3161. doi: 10.3324/haematol.2019.241745. Haematologica. 2021. PMID: 33054105 Free PMC article.
Vasculo-toxic and pro-inflammatory action of unbound haemoglobin, haem and iron in transfusion-dependent patients with haemolytic anaemias.
Vinchi F, Sparla R, Passos ST, Sharma R, Vance SZ, Zreid HS, Juaidi H, Manwani D, Yazdanbakhsh K, Nandi V, Silva AMN, Agarvas AR, Fibach E, Belcher JD, Vercellotti GM, Ghoti H, Muckenthaler MU. Vinchi F, et al. Among authors: sparla r. Br J Haematol. 2021 May;193(3):637-658. doi: 10.1111/bjh.17361. Epub 2021 Mar 15. Br J Haematol. 2021. PMID: 33723861 Free PMC article.
Is iron deficiency caused by BMPR2 mutations or dysfunction in pulmonary arterial hypertension patients?
Theobald V, Grünig E, Benjamin N, Seyfarth HJ, Halank M, Schneider MA, Richtmann S, Kazdal D, Hinderhofer K, Xanthouli P, Egenlauf B, Harutyunova S, Hoeper MM, Jonigk D, Sparla R, Muckenthaler MU, Eichstaedt CA. Theobald V, et al. Among authors: sparla r. Pulm Circ. 2023 Jun 7;13(2):e12242. doi: 10.1002/pul2.12242. eCollection 2023 Apr. Pulm Circ. 2023. PMID: 37292089 Free PMC article.
Superparamagnetic Iron Oxide Nanoparticles Reprogram the Tumor Microenvironment and Reduce Lung Cancer Regrowth after Crizotinib Treatment.
Horvat NK, Chocarro S, Marques O, Bauer TA, Qiu R, Diaz-Jimenez A, Helm B, Chen Y, Sawall S, Sparla R, Su L, Klingmüller U, Barz M, Hentze MW, Sotillo R, Muckenthaler MU. Horvat NK, et al. Among authors: sparla r. ACS Nano. 2024 Apr 30;18(17):11025-11041. doi: 10.1021/acsnano.3c08335. Epub 2024 Apr 16. ACS Nano. 2024. PMID: 38626916 Free PMC article.
Anti-inflammatory effects of phosphatidylcholine.
Treede I, Braun A, Sparla R, Kühnel M, Giese T, Turner JR, Anes E, Kulaksiz H, Füllekrug J, Stremmel W, Griffiths G, Ehehalt R. Treede I, et al. Among authors: sparla r. J Biol Chem. 2007 Sep 14;282(37):27155-27164. doi: 10.1074/jbc.M704408200. Epub 2007 Jul 18. J Biol Chem. 2007. PMID: 17636253 Free PMC article.
12 results