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The Transcription Factor ZNF683/HOBIT Regulates Human NK-Cell Development.
Post M, Cuapio A, Osl M, Lehmann D, Resch U, Davies DM, Bilban M, Schlechta B, Eppel W, Nathwani A, Stoiber D, Spanholtz J, Casanova E, Hofer E. Post M, et al. Among authors: spanholtz j. Front Immunol. 2017 May 15;8:535. doi: 10.3389/fimmu.2017.00535. eCollection 2017. Front Immunol. 2017. PMID: 28555134 Free PMC article.
Ex vivo generated natural killer cells acquire typical natural killer receptors and display a cytotoxic gene expression profile similar to peripheral blood natural killer cells.
Lehmann D, Spanholtz J, Osl M, Tordoir M, Lipnik K, Bilban M, Schlechta B, Dolstra H, Hofer E. Lehmann D, et al. Among authors: spanholtz j. Stem Cells Dev. 2012 Nov 1;21(16):2926-38. doi: 10.1089/scd.2011.0659. Epub 2012 Jul 17. Stem Cells Dev. 2012. PMID: 22571679 Free PMC article.
Allogeneic NK cells induce the in vitro activation of monocyte-derived and conventional type-2 dendritic cells and trigger an inflammatory response under cancer-associated conditions.
Toffoli EC, van Vliet AA, Forbes C, Arns AJ, Verheul HWM, Tuynman J, van der Vliet HJ, Spanholtz J, de Gruijl TD. Toffoli EC, et al. Among authors: spanholtz j. Clin Exp Immunol. 2024 Apr 23;216(2):159-171. doi: 10.1093/cei/uxae007. Clin Exp Immunol. 2024. PMID: 38330230 Free PMC article.
Advances in clinical NK cell studies: Donor selection, manufacturing and quality control.
Koehl U, Kalberer C, Spanholtz J, Lee DA, Miller JS, Cooley S, Lowdell M, Uharek L, Klingemann H, Curti A, Leung W, Alici E. Koehl U, et al. Among authors: spanholtz j. Oncoimmunology. 2015 Nov 11;5(4):e1115178. doi: 10.1080/2162402X.2015.1115178. eCollection 2016 Apr. Oncoimmunology. 2015. PMID: 27141397 Free PMC article.
High-efficiency lysis of cervical cancer by allogeneic NK cells derived from umbilical cord progenitors is independent of HLA status.
Veluchamy JP, Heeren AM, Spanholtz J, van Eendenburg JD, Heideman DA, Kenter GG, Verheul HM, van der Vliet HJ, Jordanova ES, de Gruijl TD. Veluchamy JP, et al. Among authors: spanholtz j. Cancer Immunol Immunother. 2017 Jan;66(1):51-61. doi: 10.1007/s00262-016-1919-1. Epub 2016 Oct 25. Cancer Immunol Immunother. 2017. PMID: 27783105 Free PMC article.
34 results