Spahn CMT - Search Results

1

Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-α-MSH and setmelanotide.

Heyder NA, Kleinau G, Speck D, Schmidt A, Paisdzior S, Szczepek M, Bauer B, Koch A, Gallandi M, Kwiatkowski D, Bürger J, Mielke T, Beck-Sickinger AG, Hildebrand PW, Spahn CMT, Hilger D, Schacherl M, Biebermann H, Hilal T, Kühnen P, Kobilka BK, Scheerer P. Heyder NA, et al. Among authors: spahn cmt. Cell Res. 2021 Nov;31(11):1176-1189. doi: 10.1038/s41422-021-00569-8. Epub 2021 Sep 24. Cell Res. 2021. PMID: 34561620 Free PMC article.

2

Structure of the ribosome-bound cricket paralysis virus IRES RNA.

Schüler M, Connell SR, Lescoute A, Giesebrecht J, Dabrowski M, Schroeer B, Mielke T, Penczek PA, Westhof E, Spahn CM. Schüler M, et al. Nat Struct Mol Biol. 2006 Dec;13(12):1092-6. doi: 10.1038/nsmb1177. Epub 2006 Nov 19. Nat Struct Mol Biol. 2006. PMID: 17115051

3

Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors.

Connell SR, Takemoto C, Wilson DN, Wang H, Murayama K, Terada T, Shirouzu M, Rost M, Schüler M, Giesebrecht J, Dabrowski M, Mielke T, Fucini P, Yokoyama S, Spahn CM. Connell SR, et al. Mol Cell. 2007 Mar 9;25(5):751-64. doi: 10.1016/j.molcel.2007.01.027. Mol Cell. 2007. PMID: 17349960 Free article.

4

A dose-rate effect in single-particle electron microscopy.

Chen JZ, Sachse C, Xu C, Mielke T, Spahn CM, Grigorieff N. Chen JZ, et al. J Struct Biol. 2008 Jan;161(1):92-100. doi: 10.1016/j.jsb.2007.09.017. Epub 2007 Oct 1. J Struct Biol. 2008. PMID: 17977018 Free PMC article.

5

A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation.

Connell SR, Topf M, Qin Y, Wilson DN, Mielke T, Fucini P, Nierhaus KH, Spahn CM. Connell SR, et al. Nat Struct Mol Biol. 2008 Sep;15(9):910-5. doi: 10.1038/nsmb.1469. Nat Struct Mol Biol. 2008. PMID: 19172743

6

GTPase activation of elongation factor EF-Tu by the ribosome during decoding.

Schuette JC, Murphy FV 4th, Kelley AC, Weir JR, Giesebrecht J, Connell SR, Loerke J, Mielke T, Zhang W, Penczek PA, Ramakrishnan V, Spahn CM. Schuette JC, et al. EMBO J. 2009 Mar 18;28(6):755-65. doi: 10.1038/emboj.2009.26. Epub 2009 Feb 19. EMBO J. 2009. PMID: 19229291 Free PMC article.

7

Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites.

Ratje AH, Loerke J, Mikolajka A, Brünner M, Hildebrand PW, Starosta AL, Dönhöfer A, Connell SR, Fucini P, Mielke T, Whitford PC, Onuchic JN, Yu Y, Sanbonmatsu KY, Hartmann RK, Penczek PA, Wilson DN, Spahn CM. Ratje AH, et al. Nature. 2010 Dec 2;468(7324):713-6. doi: 10.1038/nature09547. Nature. 2010. PMID: 21124459 Free PMC article.

8

Structural basis for the binding of IRES RNAs to the head of the ribosomal 40S subunit.

Muhs M, Yamamoto H, Ismer J, Takaku H, Nashimoto M, Uchiumi T, Nakashima N, Mielke T, Hildebrand PW, Nierhaus KH, Spahn CM. Muhs M, et al. Nucleic Acids Res. 2011 Jul;39(12):5264-75. doi: 10.1093/nar/gkr114. Epub 2011 Mar 4. Nucleic Acids Res. 2011. PMID: 21378123 Free PMC article.

9

The crystal structure of an oxygen-tolerant hydrogenase uncovers a novel iron-sulphur centre.

Fritsch J, Scheerer P, Frielingsdorf S, Kroschinsky S, Friedrich B, Lenz O, Spahn CM. Fritsch J, et al. Nature. 2011 Oct 16;479(7372):249-52. doi: 10.1038/nature10505. Nature. 2011. PMID: 22002606

10

Structure and dynamics of the mammalian ribosomal pretranslocation complex.

Budkevich T, Giesebrecht J, Altman RB, Munro JB, Mielke T, Nierhaus KH, Blanchard SC, Spahn CM. Budkevich T, et al. Mol Cell. 2011 Oct 21;44(2):214-24. doi: 10.1016/j.molcel.2011.07.040. Mol Cell. 2011. PMID: 22017870 Free PMC article.

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