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A nanobody recognizes a unique conserved epitope and potently neutralizes SARS-CoV-2 omicron variants.
Modhiran N, Lauer SM, Amarilla AA, Hewins P, Lopes van den Broek SI, Low YS, Thakur N, Liang B, Nieto GV, Jung J, Paramitha D, Isaacs A, Sng JDJ, Song D, Jørgensen JT, Cheuquemilla Y, Bürger J, Andersen IV, Himelreichs J, Jara R, MacLoughlin R, Miranda-Chacon Z, Chana-Cuevas P, Kramer V, Spahn C, Mielke T, Khromykh AA, Munro T, Jones ML, Young PR, Chappell K, Bailey D, Kjaer A, Herth MM, Jurado KA, Schwefel D, Rojas-Fernandez A, Watterson D. Modhiran N, et al. Among authors: spahn c. iScience. 2023 Jun 9;26(7):107085. doi: 10.1016/j.isci.2023.107085. eCollection 2023 Jul 21. iScience. 2023. PMID: 37361875 Free PMC article.
Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor.
Le-Trilling VTK, Banchenko S, Paydar D, Leipe PM, Binting L, Lauer S, Graziadei A, Klingen R, Gotthold C, Bürger J, Bracht T, Sitek B, Jan Lebbink R, Malyshkina A, Mielke T, Rappsilber J, Spahn CM, Voigt S, Trilling M, Schwefel D. Le-Trilling VTK, et al. Among authors: spahn cm. EMBO J. 2023 Mar 1;42(5):e112351. doi: 10.15252/embj.2022112351. Epub 2023 Feb 10. EMBO J. 2023. PMID: 36762436 Free PMC article.
Cell-free biosynthesis combined with deep learning accelerates de novo-development of antimicrobial peptides.
Pandi A, Adam D, Zare A, Trinh VT, Schaefer SL, Burt M, Klabunde B, Bobkova E, Kushwaha M, Foroughijabbari Y, Braun P, Spahn C, Preußer C, Pogge von Strandmann E, Bode HB, von Buttlar H, Bertrams W, Jung AL, Abendroth F, Schmeck B, Hummer G, Vázquez O, Erb TJ. Pandi A, et al. Among authors: spahn c. Nat Commun. 2023 Nov 8;14(1):7197. doi: 10.1038/s41467-023-42434-9. Nat Commun. 2023. PMID: 37938588 Free PMC article.
Structure of the actively translating plant 80S ribosome at 2.2 Å resolution.
Smirnova J, Loerke J, Kleinau G, Schmidt A, Bürger J, Meyer EH, Mielke T, Scheerer P, Bock R, Spahn CMT, Zoschke R. Smirnova J, et al. Among authors: spahn cmt. Nat Plants. 2023 Jun;9(6):987-1000. doi: 10.1038/s41477-023-01407-y. Epub 2023 May 8. Nat Plants. 2023. PMID: 37156858 Free PMC article.
200 results