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The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches.
Brosig A, Fuchs J, Ipek F, Kroon C, Schrötter S, Vadhvani M, Polyzou A, Ledderose J, van Diepen M, Holzhütter HG, Trimbuch T, Gimber N, Schmoranzer J, Lieberam I, Rosenmund C, Spahn C, Scheerer P, Szczepek M, Leondaritis G, Eickholt BJ. Brosig A, et al. Among authors: spahn c. Cell Rep. 2019 Nov 12;29(7):2028-2040.e8. doi: 10.1016/j.celrep.2019.10.039. Cell Rep. 2019. PMID: 31722215 Free PMC article.
Structural snapshots of actively translating human ribosomes.
Behrmann E, Loerke J, Budkevich TV, Yamamoto K, Schmidt A, Penczek PA, Vos MR, Bürger J, Mielke T, Scheerer P, Spahn CM. Behrmann E, et al. Cell. 2015 May 7;161(4):845-57. doi: 10.1016/j.cell.2015.03.052. Cell. 2015. PMID: 25957688 Free PMC article.
Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-α-MSH and setmelanotide.
Heyder NA, Kleinau G, Speck D, Schmidt A, Paisdzior S, Szczepek M, Bauer B, Koch A, Gallandi M, Kwiatkowski D, Bürger J, Mielke T, Beck-Sickinger AG, Hildebrand PW, Spahn CMT, Hilger D, Schacherl M, Biebermann H, Hilal T, Kühnen P, Kobilka BK, Scheerer P. Heyder NA, et al. Cell Res. 2021 Nov;31(11):1176-1189. doi: 10.1038/s41422-021-00569-8. Epub 2021 Sep 24. Cell Res. 2021. PMID: 34561620 Free PMC article.
Cryo-EM captures early ribosome assembly in action.
Qin B, Lauer SM, Balke A, Vieira-Vieira CH, Bürger J, Mielke T, Selbach M, Scheerer P, Spahn CMT, Nikolay R. Qin B, et al. Nat Commun. 2023 Feb 17;14(1):898. doi: 10.1038/s41467-023-36607-9. Nat Commun. 2023. PMID: 36797249 Free PMC article.
Structure of the actively translating plant 80S ribosome at 2.2 Å resolution.
Smirnova J, Loerke J, Kleinau G, Schmidt A, Bürger J, Meyer EH, Mielke T, Scheerer P, Bock R, Spahn CMT, Zoschke R. Smirnova J, et al. Among authors: spahn cmt. Nat Plants. 2023 Jun;9(6):987-1000. doi: 10.1038/s41477-023-01407-y. Epub 2023 May 8. Nat Plants. 2023. PMID: 37156858 Free PMC article.
The complex of tmRNA-SmpB and EF-G on translocating ribosomes.
Ramrath DJ, Yamamoto H, Rother K, Wittek D, Pech M, Mielke T, Loerke J, Scheerer P, Ivanov P, Teraoka Y, Shpanchenko O, Nierhaus KH, Spahn CM. Ramrath DJ, et al. Nature. 2012 May 6;485(7399):526-9. doi: 10.1038/nature11006. Nature. 2012. PMID: 22622583
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