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Immunotherapy Using Immunogenic Mimotopes Selected by Phage Display plus Amphotericin B Inducing a Therapeutic Response in Mice Infected with Leishmania amazonensis.
Soyer TG, Ramos FF, Pereira IAG, Lage DP, Bandeira RS, de Jesus MM, Costa GP, Machado AS, Freitas CS, Vale DL, Martins VT, Galdino AS, Chávez-Fumagalli MA, Menezes-Souza D, Duarte MC, Roatt BM, Coelho EAF, Tavares GSV. Soyer TG, et al. Pathogens. 2023 Feb 14;12(2):314. doi: 10.3390/pathogens12020314. Pathogens. 2023. PMID: 36839586 Free PMC article.
A Pluronic® F127-based polymeric micelle system containing an antileishmanial molecule is immunotherapeutic and effective in the treatment against Leishmania amazonensis infection.
Tavares GSV, Mendonça DVC, Miyazaki CK, Lage DP, Soyer TG, Carvalho LM, Ottoni FM, Dias DS, Ribeiro PAF, Antinarelli LMR, Ludolf F, Duarte MC, Coimbra ES, Chávez-Fumagalli MA, Roatt BM, Menezes-Souza D, Barichello JM, Alves RJ, Coelho EAF. Tavares GSV, et al. Among authors: soyer tg. Parasitol Int. 2019 Feb;68(1):63-72. doi: 10.1016/j.parint.2018.10.005. Epub 2018 Oct 16. Parasitol Int. 2019. PMID: 30339837
In vivo antileishmanial efficacy of a naphthoquinone derivate incorporated into a Pluronic® F127-based polymeric micelle system against Leishmania amazonensis infection.
Mendonça DVC, Tavares GSV, Lage DP, Soyer TG, Carvalho LM, Dias DS, Ribeiro PAF, Ottoni FM, Antinarelli LMR, Vale DL, Ludolf F, Duarte MC, Coimbra ES, Chávez-Fumagalli MA, Roatt BM, Menezes-Souza D, Barichello JM, Alves RJ, Coelho EAF. Mendonça DVC, et al. Among authors: soyer tg. Biomed Pharmacother. 2019 Jan;109:779-787. doi: 10.1016/j.biopha.2018.10.143. Epub 2018 Nov 5. Biomed Pharmacother. 2019. PMID: 30551531 Free article.
In vitro and in vivo antileishmanial activity of a fluoroquinoline derivate against Leishmania infantum and Leishmania amazonensis species.
Tavares GSV, Mendonça DVC, Lage DP, Antinarelli LMR, Soyer TG, Senna AJS, Matos GF, Dias DS, Ribeiro PAF, Batista JPT, Poletto JM, Brandão GC, Chávez-Fumagalli MA, Pereira GR, Coimbra ES, Coelho EAF. Tavares GSV, et al. Among authors: soyer tg. Acta Trop. 2019 Mar;191:29-37. doi: 10.1016/j.actatropica.2018.12.036. Epub 2018 Dec 23. Acta Trop. 2019. PMID: 30586571
Evaluation of the in vitro and in vivo antileishmanial activity of a chloroquinolin derivative against Leishmania species capable of causing tegumentary and visceral leishmaniasis.
Soyer TG, Mendonça DVC, Tavares GSV, Lage DP, Dias DS, Ribeiro PAF, Perin L, Ludolf F, Coelho VTS, Ferreira ACG, Neves PHAS, Matos GF, Chávez-Fumagalli MA, Coimbra ES, Pereira GR, Coelho EAF, Antinarelli LMR. Soyer TG, et al. Exp Parasitol. 2019 Apr;199:30-37. doi: 10.1016/j.exppara.2019.02.019. Epub 2019 Feb 25. Exp Parasitol. 2019. PMID: 30817917
Treatment using vanillin-derived synthetic molecules incorporated into polymeric micelles is effective against infection caused by Leishmania amazonensis species.
Pereira IAG, Freitas CS, Câmara RSB, Jesus MM, Lage DP, Tavares GSV, Soyer TG, Ramos FF, Soares NP, Santiago SS, Martins VT, Vale DL, Pimenta BL, Ludolf F, Oliveira FM, Duarte MC, Chávez-Fumagalli MA, Costa AV, Gonçalves DU, Roatt BM, Teixeira RR, Coelho EAF. Pereira IAG, et al. Among authors: soyer tg. Exp Parasitol. 2024 Mar 19;260:108743. doi: 10.1016/j.exppara.2024.108743. Online ahead of print. Exp Parasitol. 2024. PMID: 38513973
Immunotherapy Combining Mimotopes Selected by Phage Display Plus Amphotericin B Is Effective for Treatment Against Visceral Leishmaniasis.
Soyer TG, Bandeira Câmara RS, Pereira IAG, Ramos FF, de Jesus MM, Ludolf F, de Paula Costa G, Lage DP, de Freitas CS, Vale DL, Pimenta BL, Martins VT, Galdino AS, Chávez-Fumagalli MA, Roatt BM, de Sousa Vieira Tavares G, Coelho EAF. Soyer TG, et al. Parasite Immunol. 2024 May;46(5):e13037. doi: 10.1111/pim.13037. Parasite Immunol. 2024. PMID: 38720446