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Menin is required for bone morphogenetic protein 2- and transforming growth factor beta-regulated osteoblastic differentiation through interaction with Smads and Runx2.
Sowa H, Kaji H, Hendy GN, Canaff L, Komori T, Sugimoto T, Chihara K. Sowa H, et al. J Biol Chem. 2004 Sep 24;279(39):40267-75. doi: 10.1074/jbc.M401312200. Epub 2004 May 18. J Biol Chem. 2004. PMID: 15150273 Free article.
Menin, the product of the multiple endocrine neoplasia type 1 (MEN1) gene, is required for commitment of multipotential mesenchymal stem cells to the osteoblast lineage, however, it inhibits their later differentiation (Sowa, H., Kaji, H., Canaff, L., Hendy, …
Menin, the product of the multiple endocrine neoplasia type 1 (MEN1) gene, is required for commitment of multipotential mesenchymal stem cel …
Menin suppresses osteoblast differentiation by antagonizing the AP-1 factor, JunD.
Naito J, Kaji H, Sowa H, Hendy GN, Sugimoto T, Chihara K. Naito J, et al. Among authors: sowa h. J Biol Chem. 2005 Feb 11;280(6):4785-91. doi: 10.1074/jbc.M408143200. Epub 2004 Nov 23. J Biol Chem. 2005. PMID: 15563473 Free article.
We have shown previously that menin is required for the commitment of multipotential mesenchymal stem cells into the osteoblast lineage in part by interacting with the bone morphogenetic protein (BMP)-2 signaling molecules Smad1/5, and the key osteoblast transcriptional regulator …
We have shown previously that menin is required for the commitment of multipotential mesenchymal stem cells into the osteoblast lineage in p …
78 results