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Preclinical development of kinetin as a safe error-prone SARS-CoV-2 antiviral able to attenuate virus-induced inflammation.
Souza TML, Pinho VD, Setim CF, Sacramento CQ, Marcon R, Fintelman-Rodrigues N, Chaves OA, Heller M, Temerozo JR, Ferreira AC, Mattos M, Momo PB, Dias SSG, Gesto JSM, Pereira-Dutra F, Viola JPB, Queiroz-Junior CM, Guimarães LC, Chaves IM, Guimarães PPG, Costa VV, Teixeira MM, Bou-Habib DC, Bozza PT, Aguillón AR, Siqueira-Junior J, Macedo-Junior S, Andrade EL, Fadanni GP, Tolouei SEL, Potrich FB, Santos AA, Marques NF, Calixto JB, Rabi JA. Souza TML, et al. Nat Commun. 2023 Jan 13;14(1):199. doi: 10.1038/s41467-023-35928-z. Nat Commun. 2023. PMID: 36639383 Free PMC article.
Characterization of HIV-1 enzyme reverse transcriptase inhibition by the compound 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid through kinetic and in silico studies.
Souza TM, Rodrigues DQ, Ferreira VF, Marques IP, da Costa Santos F, Cunha AC, de Souza MC, de Palmer Paixão Frugulhetti IC, Bou-Habib DC, Fontes CF. Souza TM, et al. Curr HIV Res. 2009 May;7(3):327-35. doi: 10.2174/157016209788347958. Curr HIV Res. 2009. PMID: 19442130
Aureonitol, a Fungi-Derived Tetrahydrofuran, Inhibits Influenza Replication by Targeting Its Surface Glycoprotein Hemagglutinin.
Sacramento CQ, Marttorelli A, Fintelman-Rodrigues N, de Freitas CS, de Melo GR, Rocha ME, Kaiser CR, Rodrigues KF, da Costa GL, Alves CM, Santos-Filho O, Barbosa JP, Souza TM. Sacramento CQ, et al. PLoS One. 2015 Oct 13;10(10):e0139236. doi: 10.1371/journal.pone.0139236. eCollection 2015. PLoS One. 2015. PMID: 26462111 Free PMC article.
103 results