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Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice.
Figueiredo CP, Barros-Aragão FGQ, Neris RLS, Frost PS, Soares C, Souza INO, Zeidler JD, Zamberlan DC, de Sousa VL, Souza AS, Guimarães ALA, Bellio M, Marcondes de Souza J, Alves-Leon SV, Neves GA, Paula-Neto HA, Castro NG, De Felice FG, Assunção-Miranda I, Clarke JR, Da Poian AT, Ferreira ST. Figueiredo CP, et al. Among authors: souza ino. Nat Commun. 2019 Sep 5;10(1):3890. doi: 10.1038/s41467-019-11866-7. Nat Commun. 2019. PMID: 31488835 Free PMC article.
Design, synthesis and evaluation of novel feruloyl-donepezil hybrids as potential multitarget drugs for the treatment of Alzheimer's disease.
Dias KS, de Paula CT, Dos Santos T, Souza IN, Boni MS, Guimarães MJ, da Silva FM, Castro NG, Neves GA, Veloso CC, Coelho MM, de Melo IS, Giusti FC, Giusti-Paiva A, da Silva ML, Dardenne LE, Guedes IA, Pruccoli L, Morroni F, Tarozzi A, Viegas C Jr. Dias KS, et al. Eur J Med Chem. 2017 Apr 21;130:440-457. doi: 10.1016/j.ejmech.2017.02.043. Epub 2017 Feb 21. Eur J Med Chem. 2017. PMID: 28282613
d-Amino acids: new clinical pathways for brain diseases.
Souza INO, Roychaudhuri R, de Belleroche J, Mothet JP. Souza INO, et al. Trends Mol Med. 2023 Dec;29(12):1014-1028. doi: 10.1016/j.molmed.2023.09.001. Epub 2023 Sep 26. Trends Mol Med. 2023. PMID: 37770379 Review.
Cardanol-derived AChE inhibitors: Towards the development of dual binding derivatives for Alzheimer's disease.
Lemes LFN, de Andrade Ramos G, de Oliveira AS, da Silva FMR, de Castro Couto G, da Silva Boni M, Guimarães MJR, Souza INO, Bartolini M, Andrisano V, do Nascimento Nogueira PC, Silveira ER, Brand GD, Soukup O, Korábečný J, Romeiro NC, Castro NG, Bolognesi ML, Romeiro LAS. Lemes LFN, et al. Among authors: souza ino. Eur J Med Chem. 2016 Jan 27;108:687-700. doi: 10.1016/j.ejmech.2015.12.024. Epub 2015 Dec 17. Eur J Med Chem. 2016. PMID: 26735910