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NFAM1 Promotes Pro-Inflammatory Cytokine Production in Mouse and Human Monocytes.
Juchem KW, Gounder AP, Gao JP, Seccareccia E, Yeddula N, Huffmaster NJ, Côté-Martin A, Fogal SE, Souza D, Wang SS, Glynn ERA, Yung I, Ritchie J, Li L, Zheng J, Mbow ML, Li J, Chanda SK. Juchem KW, et al. Among authors: souza d. Front Immunol. 2022 Jan 13;12:773445. doi: 10.3389/fimmu.2021.773445. eCollection 2021. Front Immunol. 2022. PMID: 35095847 Free PMC article.
BTK inhibition ameliorates kidney disease in spontaneous lupus nephritis.
Chalmers SA, Glynn E, Garcia SJ, Panzenbeck M, Pelletier J, Dimock J, Seccareccia E, Bosanac T, Khalil S, Harcken C, Webb D, Nabozny G, Fine JS, Souza D, Klein E, Herlitz L, Ramanujam M, Putterman C. Chalmers SA, et al. Among authors: souza d. Clin Immunol. 2018 Dec;197:205-218. doi: 10.1016/j.clim.2018.10.008. Epub 2018 Oct 16. Clin Immunol. 2018. PMID: 30339790 Free PMC article.
CCR1 plays a critical role in modulating pain through hematopoietic and non-hematopoietic cells.
Lewis ND, Muthukumarana A, Fogal SE, Corradini L, Stefanopoulos DE, Adusumalli P, Pelletier J, Panzenbeck M, Berg K, Canfield M, Cook BN, Razavi H, Kuzmich D, Anderson S, Allard D, Harrison P, Grimaldi C, Souza D, Harcken C, Fryer RM, Modis LK, Brown ML. Lewis ND, et al. Among authors: souza d. PLoS One. 2014 Aug 29;9(8):e105883. doi: 10.1371/journal.pone.0105883. eCollection 2014. PLoS One. 2014. PMID: 25170619 Free PMC article.
Kcnn4 is a regulator of macrophage multinucleation in bone homeostasis and inflammatory disease.
Kang H, Kerloc'h A, Rotival M, Xu X, Zhang Q, D'Souza Z, Kim M, Scholz JC, Ko JH, Srivastava PK, Genzen JR, Cui W, Aitman TJ, Game L, Melvin JE, Hanidu A, Dimock J, Zheng J, Souza D, Behera AK, Nabozny G, Cook HT, Bassett JH, Williams GR, Li J, Vignery A, Petretto E, Behmoaras J. Kang H, et al. Among authors: souza d, d souza z. Cell Rep. 2014 Aug 21;8(4):1210-24. doi: 10.1016/j.celrep.2014.07.032. Epub 2014 Aug 14. Cell Rep. 2014. PMID: 25131209 Free PMC article.
The oxidase activity of vascular adhesion protein-1 (VAP-1) is essential for function.
Noonan T, Lukas S, Peet GW, Pelletier J, Panzenbeck M, Hanidu A, Mazurek S, Wasti R, Rybina I, Roma T, Kronkaitis A, Shoultz A, Souza D, Jiang H, Nabozny G, Modis LK. Noonan T, et al. Among authors: souza d. Am J Clin Exp Immunol. 2013 Jun 15;2(2):172-85. Print 2013. Am J Clin Exp Immunol. 2013. PMID: 23885334 Free PMC article.
A GPBAR1 (TGR5) small molecule agonist shows specific inhibitory effects on myeloid cell activation in vitro and reduces experimental autoimmune encephalitis (EAE) in vivo.
Lewis ND, Patnaude LA, Pelletier J, Souza DJ, Lukas SM, King FJ, Hill JD, Stefanopoulos DE, Ryan K, Desai S, Skow D, Kauschke SG, Broermann A, Kuzmich D, Harcken C, Hickey ER, Modis LK. Lewis ND, et al. Among authors: souza dj. PLoS One. 2014 Jun 26;9(6):e100883. doi: 10.1371/journal.pone.0100883. eCollection 2014. PLoS One. 2014. PMID: 24967665 Free PMC article.
Indole Inhibitors of MMP-13 for Arthritic Disorders.
Taylor SJ, Abeywardane A, Liang S, Xiong Z, Proudfoot JR, Farmer BS, Gao DA, Heim-Riether A, Smith-Keenan LL, Muegge I, Yu Y, Zhang Q, Souza D, Panzenbeck M, Goldberg D, Hill-Drzewi M, Margarit M, Collins B, Li JX, Zuvela-Jelaska L, Li J, Farrow NA. Taylor SJ, et al. Among authors: souza d. ACS Omega. 2021 Jul 19;6(29):18635-18650. doi: 10.1021/acsomega.1c01320. eCollection 2021 Jul 27. ACS Omega. 2021. PMID: 34337203 Free PMC article.
Identification of highly efficacious glucocorticoid receptor agonists with a potential for reduced clinical bone side effects.
Harcken C, Riether D, Kuzmich D, Liu P, Betageri R, Ralph M, Emmanuel M, Reeves JT, Berry A, Souza D, Nelson RM, Kukulka A, Fadra TN, Zuvela-Jelaska L, Dinallo R, Bentzien J, Nabozny GH, Thomson DS. Harcken C, et al. Among authors: souza d. J Med Chem. 2014 Feb 27;57(4):1583-98. doi: 10.1021/jm4019178. Epub 2014 Feb 7. J Med Chem. 2014. PMID: 24506830
3,467 results