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Bilateral remote ischemic conditioning in children: A two-center, double-blind, randomized controlled trial in young children undergoing cardiac surgery.
Drury NE, van Doorn C, Woolley RL, Amos-Hirst RJ, Bi R, Spencer CM, Morris KP, Montgomerie J, Stickley J, Crucean A, Gill A, Hill M, Weber RJM, Najdekr L, Jankevics A, Southam AD, Lloyd GR, Jaber O, Kassai I, Pelella G, Khan NE, Botha P, Barron DJ, Madhani M, Dunn WB, Ives NJ, Kirchhof P, Jones TJ; Bilateral Remote Ischemic Conditioning in Children Trial Investigators. Drury NE, et al. Among authors: southam ad. JTCVS Open. 2024 Mar 5;18:193-208. doi: 10.1016/j.xjon.2024.02.018. eCollection 2024 Apr. JTCVS Open. 2024. PMID: 38690427 Free PMC article. Clinical Trial.
Demonstrating the reliability of in vivo metabolomics based chemical grouping: towards best practice.
Viant MR, Amstalden E, Athersuch T, Bouhifd M, Camuzeaux S, Crizer DM, Driemert P, Ebbels T, Ekman D, Flick B, Giri V, Gómez-Romero M, Haake V, Herold M, Kende A, Lai F, Leonards PEG, Lim PP, Lloyd GR, Mosley J, Namini C, Rice JR, Romano S, Sands C, Smith MJ, Sobanski T, Southam AD, Swindale L, van Ravenzwaay B, Walk T, Weber RJM, Zickgraf FM, Kamp H. Viant MR, et al. Among authors: southam ad. Arch Toxicol. 2024 Apr;98(4):1111-1123. doi: 10.1007/s00204-024-03680-y. Epub 2024 Feb 18. Arch Toxicol. 2024. PMID: 38368582 Free PMC article.
Intermittent Surface Oxygenation Results in Similar Mitochondrial Protection and Maintenance of Aerobic Metabolism as Compared to Continuous Oxygenation during Hypothermic Machine Kidney Machine Perfusion.
Darius T, Vergauwen M, Maistriaux L, Evrard R, Schlegel A, Mueller M, O'Neil D, Southam A, Aydin S, Devresse A, De Meyer M, Gianello P, Ludwig C, Dutkowski P, Mourad M. Darius T, et al. Among authors: southam a. J Clin Med. 2023 May 29;12(11):3731. doi: 10.3390/jcm12113731. J Clin Med. 2023. PMID: 37297930 Free PMC article.
Invariant NKT cells metabolically adapt to the acute myeloid leukaemia environment.
Stavrou V, Fultang L, Booth S, De Simone D, Bartnik A, Scarpa U, Gneo L, Panetti S, Potluri S, Almowaled M, Barlow J, Jankevics A, Lloyd G, Southam A, Priestman DA, Cheng P, Dunn W, Platt F, Endou H, Craddock C, Keeshan K, Mussai F, De Santo C. Stavrou V, et al. Among authors: southam a. Cancer Immunol Immunother. 2023 Mar;72(3):543-560. doi: 10.1007/s00262-022-03268-4. Epub 2022 Aug 13. Cancer Immunol Immunother. 2023. PMID: 35962843 Free PMC article.
Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached.
Wilcock DJ, Badrock AP, Wong CW, Owen R, Guerin M, Southam AD, Johnston H, Telfer BA, Fullwood P, Watson J, Ferguson H, Ferguson J, Lloyd GR, Jankevics A, Dunn WB, Wellbrock C, Lorigan P, Ceol C, Francavilla C, Smith MP, Hurlstone AFL. Wilcock DJ, et al. Among authors: southam ad. Cell Rep. 2022 Jun 21;39(12):110995. doi: 10.1016/j.celrep.2022.110995. Cell Rep. 2022. PMID: 35732120 Free PMC article.
87 results