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Actinomycin D Targets NPM1c-Primed Mitochondria to Restore PML-Driven Senescence in AML Therapy.
Wu HC, Rérolle D, Berthier C, Hleihel R, Sakamoto T, Quentin S, Benhenda S, Morganti C, Wu C, Conte L, Rimsky S, Sebert M, Clappier E, Souquere S, Gachet S, Soulier J, Durand S, Trowbridge JJ, Bénit P, Rustin P, El Hajj H, Raffoux E, Ades L, Itzykson R, Dombret H, Fenaux P, Espeli O, Kroemer G, Brunetti L, Mak TW, Lallemand-Breitenbach V, Bazarbachi A, Falini B, Ito K, Martelli MP, de Thé H. Wu HC, et al. Among authors: souquere s. Cancer Discov. 2021 Dec 1;11(12):3198-3213. doi: 10.1158/2159-8290.CD-21-0177. Cancer Discov. 2021. PMID: 34301789 Free PMC article.
Photodynamic therapy with redaporfin targets the endoplasmic reticulum and Golgi apparatus.
Gomes-da-Silva LC, Zhao L, Bezu L, Zhou H, Sauvat A, Liu P, Durand S, Leduc M, Souquere S, Loos F, Mondragón L, Sveinbjørnsson B, Rekdal Ø, Boncompain G, Perez F, Arnaut LG, Kepp O, Kroemer G. Gomes-da-Silva LC, et al. Among authors: souquere s. EMBO J. 2018 Jul 2;37(13):e98354. doi: 10.15252/embj.201798354. Epub 2018 May 28. EMBO J. 2018. PMID: 29807932 Free PMC article.
The oncolytic compound LTX-401 targets the Golgi apparatus.
Zhou H, Sauvat A, Gomes-da-Silva LC, Durand S, Forveille S, Iribarren K, Yamazaki T, Souquere S, Bezu L, Müller K, Leduc M, Liu P, Zhao L, Marabelle A, Zitvogel L, Rekdal Ø, Kepp O, Kroemer G. Zhou H, et al. Among authors: souquere s. Cell Death Differ. 2016 Dec;23(12):2031-2041. doi: 10.1038/cdd.2016.86. Epub 2016 Sep 2. Cell Death Differ. 2016. PMID: 27588704 Free PMC article.
Lethal Poisoning of Cancer Cells by Respiratory Chain Inhibition plus Dimethyl α-Ketoglutarate.
Sica V, Bravo-San Pedro JM, Izzo V, Pol J, Pierredon S, Enot D, Durand S, Bossut N, Chery A, Souquere S, Pierron G, Vartholomaiou E, Zamzami N, Soussi T, Sauvat A, Mondragón L, Kepp O, Galluzzi L, Martinou JC, Hess-Stumpp H, Ziegelbauer K, Kroemer G, Maiuri MC. Sica V, et al. Among authors: souquere s. Cell Rep. 2019 Apr 16;27(3):820-834.e9. doi: 10.1016/j.celrep.2019.03.058. Cell Rep. 2019. PMID: 30995479 Free article.
Preapoptotic chromatin condensation upstream of the mitochondrial checkpoint.
Andreau K, Castedo M, Perfettini JL, Roumier T, Pichart E, Souquere S, Vivet S, Larochette N, Kroemer G. Andreau K, et al. Among authors: souquere s. J Biol Chem. 2004 Dec 31;279(53):55937-45. doi: 10.1074/jbc.M406411200. Epub 2004 Oct 21. J Biol Chem. 2004. PMID: 15498771 Free article.
Cytopathic effects of the cytomegalovirus-encoded apoptosis inhibitory protein vMIA.
Poncet D, Pauleau AL, Szabadkai G, Vozza A, Scholz SR, Le Bras M, Brière JJ, Jalil A, Le Moigne R, Brenner C, Hahn G, Wittig I, Schägger H, Lemaire C, Bianchi K, Souquère S, Pierron G, Rustin P, Goldmacher VS, Rizzuto R, Palmieri F, Kroemer G. Poncet D, et al. Among authors: souquere s. J Cell Biol. 2006 Sep 25;174(7):985-96. doi: 10.1083/jcb.200604069. Epub 2006 Sep 18. J Cell Biol. 2006. PMID: 16982800 Free PMC article.
The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death.
González-Polo RA, Boya P, Pauleau AL, Jalil A, Larochette N, Souquère S, Eskelinen EL, Pierron G, Saftig P, Kroemer G. González-Polo RA, et al. Among authors: souquere s. J Cell Sci. 2005 Jul 15;118(Pt 14):3091-102. doi: 10.1242/jcs.02447. Epub 2005 Jun 28. J Cell Sci. 2005. PMID: 15985464
Artificial tethering of LC3 or p62 to organelles is not sufficient to trigger autophagy.
Loos F, Xie W, Sica V, Bravo-San Pedro JM, Souquère S, Pierron G, Lachkar S, Sauvat A, Petrazzuolo A, Jimenez AJ, Perez F, Maiuri MC, Kepp O, Kroemer G. Loos F, et al. Among authors: souquere s. Cell Death Dis. 2019 Oct 10;10(10):771. doi: 10.1038/s41419-019-2011-5. Cell Death Dis. 2019. PMID: 31601788 Free PMC article.
66 results