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The HelQ human DNA repair helicase utilizes a PWI-like domain for DNA loading through interaction with RPA, triggering DNA unwinding by the HelQ helicase core.
Jenkins T, Northall SJ, Ptchelkine D, Lever R, Cubbon A, Betts H, Taresco V, Cooper CDO, McHugh PJ, Soultanas P, Bolt EL. Jenkins T, et al. Among authors: soultanas p. NAR Cancer. 2021 Jan 12;3(1):zcaa043. doi: 10.1093/narcan/zcaa043. eCollection 2021 Mar. NAR Cancer. 2021. PMID: 34316696 Free PMC article.
Unwinding the 'Gordian knot' of helicase action.
Soultanas P, Wigley DB. Soultanas P, et al. Trends Biochem Sci. 2001 Jan;26(1):47-54. doi: 10.1016/s0968-0004(00)01734-5. Trends Biochem Sci. 2001. PMID: 11165517 Review.
Molecular dynamics simulations of a helicase.
Cox K, Watson T, Soultanas P, Hirst JD. Cox K, et al. Among authors: soultanas p. Proteins. 2003 Aug 1;52(2):254-62. doi: 10.1002/prot.10400. Proteins. 2003. PMID: 12833548 Free PMC article.
73 results