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Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders.
Aiyar RS, Bohnert M, Duvezin-Caubet S, Voisset C, Gagneur J, Fritsch ES, Couplan E, von der Malsburg K, Funaya C, Soubigou F, Courtin F, Suresh S, Kucharczyk R, Evrard J, Antony C, St Onge RP, Blondel M, di Rago JP, van der Laan M, Steinmetz LM. Aiyar RS, et al. Among authors: soubigou f. Nat Commun. 2014 Dec 18;5:5585. doi: 10.1038/ncomms6585. Nat Commun. 2014. PMID: 25519239 Free PMC article.
A yeast-based assay identifies drugs active against human mitochondrial disorders.
Couplan E, Aiyar RS, Kucharczyk R, Kabala A, Ezkurdia N, Gagneur J, St Onge RP, Salin B, Soubigou F, Le Cann M, Steinmetz LM, di Rago JP, Blondel M. Couplan E, et al. Among authors: soubigou f. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):11989-94. doi: 10.1073/pnas.1101478108. Epub 2011 Jun 29. Proc Natl Acad Sci U S A. 2011. PMID: 21715656 Free PMC article.
Anti-prion Drugs Targeting the Protein Folding Activity of the Ribosome Reduce PABPN1 Aggregation.
Bamia A, Sinane M, Naït-Saïdi R, Dhiab J, Keruzoré M, Nguyen PH, Bertho A, Soubigou F, Halliez S, Blondel M, Trollet C, Simonelig M, Friocourt G, Béringue V, Bihel F, Voisset C. Bamia A, et al. Among authors: soubigou f. Neurotherapeutics. 2021 Apr;18(2):1137-1150. doi: 10.1007/s13311-020-00992-6. Epub 2021 Feb 2. Neurotherapeutics. 2021. PMID: 33533011 Free PMC article.
The toll-like receptor agonist imiquimod is active against prions.
Oumata N, Nguyen PH, Beringue V, Soubigou F, Pang Y, Desban N, Massacrier C, Morel Y, Paturel C, Contesse MA, Bouaziz S, Sanyal S, Galons H, Blondel M, Voisset C. Oumata N, et al. Among authors: soubigou f. PLoS One. 2013 Aug 16;8(8):e72112. doi: 10.1371/journal.pone.0072112. eCollection 2013. PLoS One. 2013. PMID: 23977222 Free PMC article.
A new genotoxicity assay based on p53 target gene induction.
Zerdoumi Y, Kasper E, Soubigou F, Adriouch S, Bougeard G, Frebourg T, Flaman JM. Zerdoumi Y, et al. Among authors: soubigou f. Mutat Res Genet Toxicol Environ Mutagen. 2015 Aug;789-790:28-35. doi: 10.1016/j.mrgentox.2015.05.010. Epub 2015 May 29. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 26232255
12 results