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Inactivation of Proprotein Convertases in T Cells Inhibits PD-1 Expression and Creates a Favorable Immune Microenvironment in Colorectal Cancer.
Tomé M, Pappalardo A, Soulet F, López JJ, Olaizola J, Leger Y, Dubreuil M, Mouchard A, Fessart D, Delom F, Pitard V, Bechade D, Fonck M, Rosado JA, Ghiringhelli F, Déchanet-Merville J, Soubeyran I, Siegfried G, Evrard S, Khatib AM. Tomé M, et al. Among authors: soubeyran i. Cancer Res. 2019 Oct 1;79(19):5008-5021. doi: 10.1158/0008-5472.CAN-19-0086. Epub 2019 Jul 29. Cancer Res. 2019. PMID: 31358531
All-trans retinoic acid targets gastric cancer stem cells and inhibits patient-derived gastric carcinoma tumor growth.
Nguyen PH, Giraud J, Staedel C, Chambonnier L, Dubus P, Chevret E, Bœuf H, Gauthereau X, Rousseau B, Fevre M, Soubeyran I, Belleannée G, Evrard S, Collet D, Mégraud F, Varon C. Nguyen PH, et al. Among authors: soubeyran i. Oncogene. 2016 Oct 27;35(43):5619-5628. doi: 10.1038/onc.2016.87. Epub 2016 May 9. Oncogene. 2016. PMID: 27157616
Characterization of Biomarkers of Tumorigenic and Chemoresistant Cancer Stem Cells in Human Gastric Carcinoma.
Nguyen PH, Giraud J, Chambonnier L, Dubus P, Wittkop L, Belleannée G, Collet D, Soubeyran I, Evrard S, Rousseau B, Senant-Dugot N, Mégraud F, Mazurier F, Varon C. Nguyen PH, et al. Among authors: soubeyran i. Clin Cancer Res. 2017 Mar 15;23(6):1586-1597. doi: 10.1158/1078-0432.CCR-15-2157. Epub 2016 Sep 12. Clin Cancer Res. 2017. PMID: 27620279
ELA/APELA precursor cleaved by furin displays tumor suppressor function in renal cell carcinoma through mTORC1 activation.
Soulet F, Bodineau C, Hooks KB, Descarpentrie J, Alves I, Dubreuil M, Mouchard A, Eugenie M, Hoepffner JL, López JJ, Rosado JA, Soubeyran I, Tomé M, Durán RV, Nikolski M, Villoutreix BO, Evrard S, Siegfried G, Khatib AM. Soulet F, et al. Among authors: soubeyran i. JCI Insight. 2020 Jul 23;5(14):e129070. doi: 10.1172/jci.insight.129070. JCI Insight. 2020. PMID: 32516140 Free PMC article.
Prognostic Role of Inflammasome Components in Human Colorectal Cancer.
Domblides C, Soubeyran I, Lartigue L, Mahouche I, Lefort F, Velasco V, Barnetche T, Blanco P, Déchanet-Merville J, Faustin B. Domblides C, et al. Among authors: soubeyran i. Cancers (Basel). 2020 Nov 24;12(12):3500. doi: 10.3390/cancers12123500. Cancers (Basel). 2020. PMID: 33255437 Free PMC article.
Regorafenib-Avelumab Combination in Patients with Microsatellite Stable Colorectal Cancer (REGOMUNE): A Single-arm, Open-label, Phase II Trial.
Cousin S, Cantarel C, Guegan JP, Gomez-Roca C, Metges JP, Adenis A, Pernot S, Bellera C, Kind M, Auzanneau C, Le Loarer F, Soubeyran I, Bessede A, Italiano A. Cousin S, et al. Among authors: soubeyran i. Clin Cancer Res. 2021 Apr 15;27(8):2139-2147. doi: 10.1158/1078-0432.CCR-20-3416. Epub 2021 Jan 25. Clin Cancer Res. 2021. PMID: 33495314 Clinical Trial.
Human γδ T cell sensing of AMPK-dependent metabolic tumor reprogramming through TCR recognition of EphA2.
Harly C, Joyce SP, Domblides C, Bachelet T, Pitard V, Mannat C, Pappalardo A, Couzi L, Netzer S, Massara L, Obre E, Hawchar O, Lartigue L, Claverol S, Cano C, Moreau JF, Mahouche I, Soubeyran I, Rossignol R, Viollet B, Willcox CR, Mohammed F, Willcox BE, Faustin B, Déchanet-Merville J. Harly C, et al. Among authors: soubeyran i. Sci Immunol. 2021 Jul 30;6(61):eaba9010. doi: 10.1126/sciimmunol.aba9010. Sci Immunol. 2021. PMID: 34330813
119 results