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Hydroxy metabolites of the Alzheimer's drug candidate 3-[(2,4-dimethoxy)benzylidene]-anabaseine dihydrochloride (GTS-21): their molecular properties, interactions with brain nicotinic receptors, and brain penetration.
Kem WR, Mahnir VM, Prokai L, Papke RL, Cao X, LeFrancois S, Wildeboer K, Prokai-Tatrai K, Porter-Papke J, Soti F. Kem WR, et al. Among authors: soti f. Mol Pharmacol. 2004 Jan;65(1):56-67. doi: 10.1124/mol.65.1.56. Mol Pharmacol. 2004. PMID: 14722237
Initial phase 2 trial of a nicotinic agonist in schizophrenia.
Freedman R, Olincy A, Buchanan RW, Harris JG, Gold JM, Johnson L, Allensworth D, Guzman-Bonilla A, Clement B, Ball MP, Kutnick J, Pender V, Martin LF, Stevens KE, Wagner BD, Zerbe GO, Soti F, Kem WR. Freedman R, et al. Among authors: soti f. Am J Psychiatry. 2008 Aug;165(8):1040-7. doi: 10.1176/appi.ajp.2008.07071135. Epub 2008 Apr 1. Am J Psychiatry. 2008. PMID: 18381905 Free PMC article. Clinical Trial.
Functional magnetic resonance imaging of effects of a nicotinic agonist in schizophrenia.
Tregellas JR, Olincy A, Johnson L, Tanabe J, Shatti S, Martin LF, Singel D, Du YP, Soti F, Kem WR, Freedman R. Tregellas JR, et al. Among authors: soti f. Neuropsychopharmacology. 2010 Mar;35(4):938-42. doi: 10.1038/npp.2009.196. Epub 2009 Dec 2. Neuropsychopharmacology. 2010. PMID: 19956085 Free PMC article. Clinical Trial.
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