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Sarcoplasmic reticulum calcium leak contributes to arrhythmia but not to heart failure progression.
Mohamed BA, Hartmann N, Tirilomis P, Sekeres K, Li W, Neef S, Richter C, Zeisberg EM, Kattner L, Didié M, Guan K, Schmitto JD, Lehnart SE, Luther S, Voigt N, Seidler T, Sossalla S, Hasenfuss G, Toischer K. Mohamed BA, et al. Among authors: sossalla s. Sci Transl Med. 2018 Sep 12;10(458):eaan0724. doi: 10.1126/scitranslmed.aan0724. Sci Transl Med. 2018. PMID: 30209242
An Alternative Mechanism of Subcellular Iron Uptake Deficiency in Cardiomyocytes.
Dai Y, Ignatyeva N, Xu H, Wali R, Toischer K, Brandenburg S, Lenz C, Pronto J, Fakuade FE, Sossalla S, Zeisberg EM, Janshoff A, Kutschka I, Voigt N, Urlaub H, Rasmussen TB, Mogensen J, Lehnart SE, Hasenfuss G, Ebert A. Dai Y, et al. Among authors: sossalla s. Circ Res. 2023 Jul 7;133(2):e19-e46. doi: 10.1161/CIRCRESAHA.122.321157. Epub 2023 Jun 14. Circ Res. 2023. PMID: 37313752 Free article.
Differential cardiac remodeling in preload versus afterload.
Toischer K, Rokita AG, Unsöld B, Zhu W, Kararigas G, Sossalla S, Reuter SP, Becker A, Teucher N, Seidler T, Grebe C, Preuss L, Gupta SN, Schmidt K, Lehnart SE, Krüger M, Linke WA, Backs J, Regitz-Zagrosek V, Schäfer K, Field LJ, Maier LS, Hasenfuss G. Toischer K, et al. Among authors: sossalla s. Circulation. 2010 Sep 7;122(10):993-1003. doi: 10.1161/CIRCULATIONAHA.110.943431. Epub 2010 Aug 23. Circulation. 2010. PMID: 20733099 Free PMC article.
Calcium/Calmodulin-Dependent Protein Kinase II Activity Persists During Chronic β-Adrenoceptor Blockade in Experimental and Human Heart Failure.
Dewenter M, Neef S, Vettel C, Lämmle S, Beushausen C, Zelarayan LC, Katz S, von der Lieth A, Meyer-Roxlau S, Weber S, Wieland T, Sossalla S, Backs J, Brown JH, Maier LS, El-Armouche A. Dewenter M, et al. Among authors: sossalla s. Circ Heart Fail. 2017 May;10(5):e003840. doi: 10.1161/CIRCHEARTFAILURE.117.003840. Circ Heart Fail. 2017. PMID: 28487342 Free PMC article.
Empagliflozin reduces Ca/calmodulin-dependent kinase II activity in isolated ventricular cardiomyocytes.
Mustroph J, Wagemann O, Lücht CM, Trum M, Hammer KP, Sag CM, Lebek S, Tarnowski D, Reinders J, Perbellini F, Terracciano C, Schmid C, Schopka S, Hilker M, Zausig Y, Pabel S, Sossalla ST, Schweda F, Maier LS, Wagner S. Mustroph J, et al. Among authors: sossalla st. ESC Heart Fail. 2018 Aug;5(4):642-648. doi: 10.1002/ehf2.12336. ESC Heart Fail. 2018. PMID: 30117720 Free PMC article.
Empagliflozin directly improves diastolic function in human heart failure.
Pabel S, Wagner S, Bollenberg H, Bengel P, Kovács Á, Schach C, Tirilomis P, Mustroph J, Renner A, Gummert J, Fischer T, Van Linthout S, Tschöpe C, Streckfuss-Bömeke K, Hasenfuss G, Maier LS, Hamdani N, Sossalla S. Pabel S, et al. Among authors: sossalla s. Eur J Heart Fail. 2018 Dec;20(12):1690-1700. doi: 10.1002/ejhf.1328. Epub 2018 Oct 17. Eur J Heart Fail. 2018. PMID: 30328645 Free article.
KLF15-Wnt-Dependent Cardiac Reprogramming Up-Regulates SHISA3 in the Mammalian Heart.
Noack C, Iyer LM, Liaw NY, Schoger E, Khadjeh S, Wagner E, Woelfer M, Zafiriou MP, Milting H, Sossalla S, Streckfuss-Boemeke K, Hasenfuß G, Zimmermann WH, Zelarayán LC. Noack C, et al. Among authors: sossalla s. J Am Coll Cardiol. 2019 Oct 8;74(14):1804-1819. doi: 10.1016/j.jacc.2019.07.076. J Am Coll Cardiol. 2019. PMID: 31582141 Free article.
CaM kinase II regulates cardiac hemoglobin expression through histone phosphorylation upon sympathetic activation.
Saadatmand AR, Sramek V, Weber S, Finke D, Dewenter M, Sticht C, Gretz N, Wüstemann T, Hagenmueller M, Kuenzel SR, Meyer-Roxlau S, Kramer M, Sossalla S, Lehmann LH, Kämmerer S, Backs J, El-Armouche A. Saadatmand AR, et al. Among authors: sossalla s. Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):22282-22287. doi: 10.1073/pnas.1816521116. Epub 2019 Oct 16. Proc Natl Acad Sci U S A. 2019. PMID: 31619570 Free PMC article.
191 results