Sosnick TR - Search Results

1

Development of in vivo HDX-MS with applications to a TonB-dependent transporter and other proteins.

Lin X, Zmyslowski AM, Gagnon IA, Nakamoto RK, Sosnick TR. Lin X, et al. Among authors: sosnick tr. Protein Sci. 2022 Sep;31(9):e4402. doi: 10.1002/pro.4402. Protein Sci. 2022. PMID: 36040258 Free PMC article.

2

Introduction of a polar core into the de novo designed protein Top7.

Basanta B, Chan KK, Barth P, King T, Sosnick TR, Hinshaw JR, Liu G, Everett JK, Xiao R, Montelione GT, Baker D. Basanta B, et al. Among authors: sosnick tr. Protein Sci. 2016 Jul;25(7):1299-307. doi: 10.1002/pro.2899. Epub 2016 Mar 7. Protein Sci. 2016. PMID: 26873166 Free PMC article.

3

Cooperative folding near the downhill limit determined with amino acid resolution by hydrogen exchange.

Yu W, Baxa MC, Gagnon I, Freed KF, Sosnick TR. Yu W, et al. Among authors: sosnick tr. Proc Natl Acad Sci U S A. 2016 Apr 26;113(17):4747-52. doi: 10.1073/pnas.1522500113. Epub 2016 Apr 13. Proc Natl Acad Sci U S A. 2016. PMID: 27078098 Free PMC article.

4

Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water.

Riback JA, Bowman MA, Zmyslowski AM, Knoverek CR, Jumper JM, Hinshaw JR, Kaye EB, Freed KF, Clark PL, Sosnick TR. Riback JA, et al. Among authors: sosnick tr. Science. 2017 Oct 13;358(6360):238-241. doi: 10.1126/science.aan5774. Science. 2017. PMID: 29026044 Free PMC article.

5

Response to Comment on "Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water".

Riback JA, Bowman MA, Zmyslowski A, Knoverek CR, Jumper J, Kaye EB, Freed KF, Clark PL, Sosnick TR. Riback JA, et al. Among authors: sosnick tr. Science. 2018 Aug 31;361(6405):eaar7949. doi: 10.1126/science.aar7949. Science. 2018. PMID: 30166460

6

Commonly used FRET fluorophores promote collapse of an otherwise disordered protein.

Riback JA, Bowman MA, Zmyslowski AM, Plaxco KW, Clark PL, Sosnick TR. Riback JA, et al. Among authors: sosnick tr. Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):8889-8894. doi: 10.1073/pnas.1813038116. Epub 2019 Apr 16. Proc Natl Acad Sci U S A. 2019. PMID: 30992378 Free PMC article.

7

Folding and misfolding of potassium channel monomers during assembly and tetramerization.

Song KC, Molina AV, Chen R, Gagnon IA, Koh YH, Roux B, Sosnick TR. Song KC, et al. Among authors: sosnick tr. Proc Natl Acad Sci U S A. 2021 Aug 24;118(34):e2103674118. doi: 10.1073/pnas.2103674118. Proc Natl Acad Sci U S A. 2021. PMID: 34413192 Free PMC article.

8

Prediction and Validation of a Protein's Free Energy Surface Using Hydrogen Exchange and (Importantly) Its Denaturant Dependence.

Peng X, Baxa M, Faruk N, Sachleben JR, Pintscher S, Gagnon IA, Houliston S, Arrowsmith CH, Freed KF, Rocklin GJ, Sosnick TR. Peng X, et al. Among authors: sosnick tr. J Chem Theory Comput. 2022 Jan 11;18(1):550-561. doi: 10.1021/acs.jctc.1c00960. Epub 2021 Dec 22. J Chem Theory Comput. 2022. PMID: 34936354 Free PMC article.

9

HDX-MS performed on BtuB in E. coli outer membranes delineates the luminal domain's allostery and unfolding upon B12 and TonB binding.

Zmyslowski AM, Baxa MC, Gagnon IA, Sosnick TR. Zmyslowski AM, et al. Among authors: sosnick tr. Proc Natl Acad Sci U S A. 2022 May 17;119(20):e2119436119. doi: 10.1073/pnas.2119436119. Epub 2022 May 12. Proc Natl Acad Sci U S A. 2022. PMID: 35549554 Free PMC article.

10

Folding of Prestin's Anion-Binding Site and the Mechanism of Outer Hair Cell Electromotility.

Lin X, Haller P, Bavi N, Faruk N, Perozo E, Sosnick TR. Lin X, et al. Among authors: sosnick tr. bioRxiv [Preprint]. 2023 Oct 1:2023.02.27.530320. doi: 10.1101/2023.02.27.530320. bioRxiv. 2023. PMID: 36909622 Free PMC article. Updated. Preprint.

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