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Autophagy impairment in liver CD11c+ cells promotes non-alcoholic fatty liver disease through production of IL-23.
Galle-Treger L, Helou DG, Quach C, Howard E, Hurrell BP, Muench GRA, Shafiei-Jahani P, Painter JD, Iorga A, Dara L, Emamaullee J, Golden-Mason L, Rosen HR, Soroosh P, Akbari O. Galle-Treger L, et al. Among authors: soroosh p. Nat Commun. 2022 Mar 17;13(1):1440. doi: 10.1038/s41467-022-29174-y. Nat Commun. 2022. PMID: 35301333 Free PMC article.
Lack of autophagy induces steroid-resistant airway inflammation.
Suzuki Y, Maazi H, Sankaranarayanan I, Lam J, Khoo B, Soroosh P, Barbers RG, James Ou JH, Jung JU, Akbari O. Suzuki Y, et al. Among authors: soroosh p. J Allergy Clin Immunol. 2016 May;137(5):1382-1389.e9. doi: 10.1016/j.jaci.2015.09.033. Epub 2015 Nov 14. J Allergy Clin Immunol. 2016. PMID: 26589586 Free PMC article.
Type 2 innate lymphoid cell suppression by regulatory T cells attenuates airway hyperreactivity and requires inducible T-cell costimulator-inducible T-cell costimulator ligand interaction.
Rigas D, Lewis G, Aron JL, Wang B, Banie H, Sankaranarayanan I, Galle-Treger L, Maazi H, Lo R, Freeman GJ, Sharpe AH, Soroosh P, Akbari O. Rigas D, et al. Among authors: soroosh p. J Allergy Clin Immunol. 2017 May;139(5):1468-1477.e2. doi: 10.1016/j.jaci.2016.08.034. Epub 2016 Oct 4. J Allergy Clin Immunol. 2017. PMID: 27717665 Free PMC article.
Group 2 innate lymphoid cells are elevated and activated in chronic rhinosinusitis with nasal polyps.
Poposki JA, Klingler AI, Tan BK, Soroosh P, Banie H, Lewis G, Hulse KE, Stevens WW, Peters AT, Grammer LC, Schleimer RP, Welch KC, Smith SS, Conley DB, Raviv JR, Karras JG, Akbari O, Kern RC, Kato A. Poposki JA, et al. Among authors: soroosh p. Immun Inflamm Dis. 2017 Sep;5(3):233-243. doi: 10.1002/iid3.161. Epub 2017 Apr 19. Immun Inflamm Dis. 2017. PMID: 28474861 Free PMC article.
IL-10, TGF-β, and glucocorticoid prevent the production of type 2 cytokines in human group 2 innate lymphoid cells.
Ogasawara N, Poposki JA, Klingler AI, Tan BK, Weibman AR, Hulse KE, Stevens WW, Peters AT, Grammer LC, Schleimer RP, Welch KC, Smith SS, Conley DB, Raviv JR, Soroosh P, Akbari O, Himi T, Kern RC, Kato A. Ogasawara N, et al. Among authors: soroosh p. J Allergy Clin Immunol. 2018 Mar;141(3):1147-1151.e8. doi: 10.1016/j.jaci.2017.09.025. Epub 2017 Oct 23. J Allergy Clin Immunol. 2018. PMID: 29074458 Free PMC article. No abstract available.
Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes.
Galle-Treger L, Sankaranarayanan I, Hurrell BP, Howard E, Lo R, Maazi H, Lewis G, Banie H, Epstein AL, Hu P, Rehan VK, Gilliland FD, Allayee H, Soroosh P, Sharpe AH, Akbari O. Galle-Treger L, et al. Among authors: soroosh p. Nat Commun. 2019 Feb 12;10(1):713. doi: 10.1038/s41467-019-08449-x. Nat Commun. 2019. PMID: 30755607 Free PMC article.
Dietary Fiber-Induced Microbial Short Chain Fatty Acids Suppress ILC2-Dependent Airway Inflammation.
Lewis G, Wang B, Shafiei Jahani P, Hurrell BP, Banie H, Aleman Muench GR, Maazi H, Helou DG, Howard E, Galle-Treger L, Lo R, Santosh S, Baltus A, Bongers G, San-Mateo L, Gilliland FD, Rehan VK, Soroosh P, Akbari O. Lewis G, et al. Among authors: soroosh p. Front Immunol. 2019 Sep 18;10:2051. doi: 10.3389/fimmu.2019.02051. eCollection 2019. Front Immunol. 2019. PMID: 31620118 Free PMC article.
45 results