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mRNA-LNP vaccines tuned for systemic immunization induce strong antitumor immunity by engaging splenic immune cells.
Bevers S, Kooijmans SAA, Van de Velde E, Evers MJW, Seghers S, Gitz-Francois JJJM, van Kronenburg NCH, Fens MHAM, Mastrobattista E, Hassler L, Sork H, Lehto T, Ahmed KE, El Andaloussi S, Fiedler K, Breckpot K, Maes M, Van Hoorick D, Bastogne T, Schiffelers RM, De Koker S. Bevers S, et al. Among authors: sork h. Mol Ther. 2022 Sep 7;30(9):3078-3094. doi: 10.1016/j.ymthe.2022.07.007. Epub 2022 Jul 12. Mol Ther. 2022. PMID: 35821637 Free PMC article.
A peptide-based vector for efficient gene transfer in vitro and in vivo.
Lehto T, Simonson OE, Mäger I, Ezzat K, Sork H, Copolovici DM, Viola JR, Zaghloul EM, Lundin P, Moreno PM, Mäe M, Oskolkov N, Suhorutšenko J, Smith CI, Andaloussi SE. Lehto T, et al. Among authors: sork h. Mol Ther. 2011 Aug;19(8):1457-67. doi: 10.1038/mt.2011.10. Epub 2011 Feb 22. Mol Ther. 2011. PMID: 21343913 Free PMC article.
Lipid-based Transfection Reagents Exhibit Cryo-induced Increase in Transfection Efficiency.
Sork H, Nordin JZ, Turunen JJ, Wiklander OP, Bestas B, Zaghloul EM, Margus H, Padari K, Duru AD, Corso G, Bost J, Vader P, Pooga M, Smith CE, Wood MJ, Schiffelers RM, Hällbrink M, Andaloussi SE. Sork H, et al. Mol Ther Nucleic Acids. 2016 Mar 8;5(3):e290. doi: 10.1038/mtna.2016.8. Mol Ther Nucleic Acids. 2016. PMID: 27111416 Free PMC article.
Comprehensive RNA-Sequencing Analysis in Serum and Muscle Reveals Novel Small RNA Signatures with Biomarker Potential for DMD.
Coenen-Stass AML, Sork H, Gatto S, Godfrey C, Bhomra A, Krjutškov K, Hart JR, Westholm JO, O'Donovan L, Roos A, Lochmüller H, Puri PL, El Andaloussi S, Wood MJA, Roberts TC. Coenen-Stass AML, et al. Among authors: sork h. Mol Ther Nucleic Acids. 2018 Dec 7;13:1-15. doi: 10.1016/j.omtn.2018.08.005. Epub 2018 Aug 17. Mol Ther Nucleic Acids. 2018. PMID: 30219269 Free PMC article.
Identification of storage conditions stabilizing extracellular vesicles preparations.
Görgens A, Corso G, Hagey DW, Jawad Wiklander R, Gustafsson MO, Felldin U, Lee Y, Bostancioglu RB, Sork H, Liang X, Zheng W, Mohammad DK, van de Wakker SI, Vader P, Zickler AM, Mamand DR, Ma L, Holme MN, Stevens MM, Wiklander OPB, El Andaloussi S. Görgens A, et al. Among authors: sork h. J Extracell Vesicles. 2022 Jun;11(6):e12238. doi: 10.1002/jev2.12238. J Extracell Vesicles. 2022. PMID: 35716060 Free PMC article.
Novel Orthogonally Hydrocarbon-Modified Cell-Penetrating Peptide Nanoparticles Mediate Efficient Delivery of Splice-Switching Antisense Oligonucleotides In Vitro and In Vivo.
Bazaz S, Lehto T, Tops R, Gissberg O, Gupta D, Bestas B, Bost J, Wiklander OPB, Sork H, Zaghloul EM, Mamand DR, Hällbrink M, Sillard R, Saher O, Ezzat K, Smith CIE, Andaloussi SE, Lehto T. Bazaz S, et al. Among authors: sork h. Biomedicines. 2021 Aug 19;9(8):1046. doi: 10.3390/biomedicines9081046. Biomedicines. 2021. PMID: 34440250 Free PMC article.
Amelioration of systemic inflammation via the display of two different decoy protein receptors on extracellular vesicles.
Gupta D, Wiklander OPB, Görgens A, Conceição M, Corso G, Liang X, Seow Y, Balusu S, Feldin U, Bostancioglu B, Jawad R, Mamand DR, Lee YXF, Hean J, Mäger I, Roberts TC, Gustafsson M, Mohammad DK, Sork H, Backlund A, Lundin P, de Fougerolles A, Smith CIE, Wood MJA, Vandenbroucke RE, Nordin JZ, El-Andaloussi S. Gupta D, et al. Among authors: sork h. Nat Biomed Eng. 2021 Sep;5(9):1084-1098. doi: 10.1038/s41551-021-00792-z. Epub 2021 Oct 6. Nat Biomed Eng. 2021. PMID: 34616047
16 results