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Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma.
Donovan LK, Delaidelli A, Joseph SK, Bielamowicz K, Fousek K, Holgado BL, Manno A, Srikanthan D, Gad AZ, Van Ommeren R, Przelicki D, Richman C, Ramaswamy V, Daniels C, Pallota JG, Douglas T, Joynt ACM, Haapasalo J, Nor C, Vladoiu MC, Kuzan-Fischer CM, Garzia L, Mack SC, Varadharajan S, Baker ML, Hendrikse L, Ly M, Kharas K, Balin P, Wu X, Qin L, Huang N, Stucklin AG, Morrissy AS, Cavalli FMG, Luu B, Suarez R, De Antonellis P, Michealraj A, Rastan A, Hegde M, Komosa M, Sirbu O, Kumar SA, Abdullaev Z, Faria CC, Yip S, Hukin J, Tabori U, Hawkins C, Aldape K, Daugaard M, Maris JM, Sorensen PH, Ahmed N, Taylor MD. Donovan LK, et al. Among authors: sorensen ph. Nat Med. 2020 May;26(5):720-731. doi: 10.1038/s41591-020-0827-2. Epub 2020 Apr 27. Nat Med. 2020. PMID: 32341580 Free PMC article.
Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes.
Daugaard M, Nitsch R, Razaghi B, McDonald L, Jarrar A, Torrino S, Castillo-Lluva S, Rotblat B, Li L, Malliri A, Lemichez E, Mettouchi A, Berman JN, Penninger JM, Sorensen PH. Daugaard M, et al. Among authors: sorensen ph. Nat Commun. 2013;4:2180. doi: 10.1038/ncomms3180. Nat Commun. 2013. PMID: 23864022 Free PMC article.
Loss of the tumor suppressor Hace1 leads to ROS-dependent glutamine addiction.
Cetinbas N, Daugaard M, Mullen AR, Hajee S, Rotblat B, Lopez A, Li A, DeBerardinis RJ, Sorensen PH. Cetinbas N, et al. Among authors: sorensen ph. Oncogene. 2015 Jul 23;34(30):4005-10. doi: 10.1038/onc.2014.316. Epub 2014 Oct 6. Oncogene. 2015. PMID: 25284589 Free PMC article.
eEF2K protects MYCN-amplified cells from starvation.
Delaidelli A, Leprivier G, Sorensen PH. Delaidelli A, et al. Among authors: sorensen ph. Cell Cycle. 2017 Sep 17;16(18):1633-1634. doi: 10.1080/15384101.2017.1355180. Epub 2017 Aug 2. Cell Cycle. 2017. PMID: 28767324 Free PMC article. No abstract available.
TEM8/ANTXR1-Specific CAR T Cells as a Targeted Therapy for Triple-Negative Breast Cancer.
Byrd TT, Fousek K, Pignata A, Szot C, Samaha H, Seaman S, Dobrolecki L, Salsman VS, Oo HZ, Bielamowicz K, Landi D, Rainusso N, Hicks J, Powell S, Baker ML, Wels WS, Koch J, Sorensen PH, Deneen B, Ellis MJ, Lewis MT, Hegde M, Fletcher BS, St Croix B, Ahmed N. Byrd TT, et al. Among authors: sorensen ph. Cancer Res. 2018 Jan 15;78(2):489-500. doi: 10.1158/0008-5472.CAN-16-1911. Epub 2017 Nov 28. Cancer Res. 2018. PMID: 29183891 Free PMC article.
The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner.
Agerbæk MØ, Bang-Christensen SR, Yang MH, Clausen TM, Pereira MA, Sharma S, Ditlev SB, Nielsen MA, Choudhary S, Gustavsson T, Sorensen PH, Meyer T, Propper D, Shamash J, Theander TG, Aicher A, Daugaard M, Heeschen C, Salanti A. Agerbæk MØ, et al. Among authors: sorensen ph. Nat Commun. 2018 Aug 16;9(1):3279. doi: 10.1038/s41467-018-05793-2. Nat Commun. 2018. PMID: 30115931 Free PMC article.
231 results