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Drug Repurposing: Deferasirox Inhibits the Anti-Apoptotic Activity of Mcl-1.
Bourafai-Aziez A, Benabderrahmane M, Paysant H, Weiswald LB, Poulain L, Carlier L, Ravault D, Jouanne M, Coadou G, Oulyadi H, Voisin-Chiret AS, Sopková-de Oliveira Santos J, Sebban M. Bourafai-Aziez A, et al. Among authors: sopkova de oliveira santos j. Drug Des Devel Ther. 2021 Dec 15;15:5035-5059. doi: 10.2147/DDDT.S323077. eCollection 2021. Drug Des Devel Ther. 2021. PMID: 34949914 Free PMC article.
Conformation control of abiotic α-helical foldamers.
Perato S, Fogha J, Sebban M, Voisin-Chiret AS, Sopkova-de Oliveira Santos J, Oulyadi H, Rault S. Perato S, et al. J Chem Inf Model. 2013 Oct 28;53(10):2671-80. doi: 10.1021/ci400365y. Epub 2013 Oct 11. J Chem Inf Model. 2013. PMID: 24032461
First evidence that oligopyridines, α-helix foldamers, inhibit Mcl-1 and sensitize ovarian carcinoma cells to Bcl-xL-targeting strategies.
Gloaguen C, Voisin-Chiret AS, Sopkova-de Oliveira Santos J, Fogha J, Gautier F, De Giorgi M, Burzicki G, Perato S, Pétigny-Lechartier C, Simonin-Le Jeune K, Brotin E, Goux D, N'Diaye M, Lambert B, Louis MH, Ligat L, Lopez F, Juin P, Bureau R, Rault S, Poulain L. Gloaguen C, et al. J Med Chem. 2015 Feb 26;58(4):1644-68. doi: 10.1021/jm500672y. Epub 2015 Feb 4. J Med Chem. 2015. PMID: 25585174
Toward Understanding Mcl-1 Promiscuous and Specific Binding Mode.
Fogha J, Marekha B, De Giorgi M, Voisin-Chiret AS, Rault S, Bureau R, Sopkova-de Oliveira Santos J. Fogha J, et al. J Chem Inf Model. 2017 Nov 27;57(11):2885-2895. doi: 10.1021/acs.jcim.7b00396. Epub 2017 Oct 27. J Chem Inf Model. 2017. PMID: 29016132
Selecting the first chemical molecule inhibitor of HSP110 for colorectal cancer therapy.
Gozzi GJ, Gonzalez D, Boudesco C, Dias AMM, Gotthard G, Uyanik B, Dondaine L, Marcion G, Hermetet F, Denis C, Hardy L, Suzanne P, Douhard R, Jego G, Dubrez L, Demidov ON, Neiers F, Briand L, Sopková-de Oliveira Santos J, Voisin-Chiret AS, Garrido C. Gozzi GJ, et al. Cell Death Differ. 2020 Jan;27(1):117-129. doi: 10.1038/s41418-019-0343-4. Epub 2019 May 8. Cell Death Differ. 2020. PMID: 31068676 Free PMC article.
Hot-Spots of Mcl-1 Protein.
Denis C, Sopková-de Oliveira Santos J, Bureau R, Voisin-Chiret AS. Denis C, et al. J Med Chem. 2020 Feb 13;63(3):928-943. doi: 10.1021/acs.jmedchem.9b00983. Epub 2019 Oct 16. J Med Chem. 2020. PMID: 31580668 Review.
Binding mode of Pyridoclax to myeloid cell leukemia-1 (Mcl-1) revealed by nuclear magnetic resonance spectroscopy, docking and molecular dynamics approaches.
Bourafai-Aziez A, Sebban M, Benabderrahmane M, Marekha B, Denis C, Paysant H, Weiswald LB, Carlier L, Bureau R, Coadou G, Ravault D, Voisin-Chiret AS, Sopková-de Oliveira Santos J, Oulyadi H. Bourafai-Aziez A, et al. J Biomol Struct Dyn. 2020 Sep;38(14):4162-4178. doi: 10.1080/07391102.2019.1680434. Epub 2019 Oct 29. J Biomol Struct Dyn. 2020. PMID: 31612791
Synthesis of Pyridoclax Analogues: Insight into Their Druggability by Investigating Their Physicochemical Properties and Interactions with Membranes.
De Pascale M, Iacopetta D, Since M, Corvaisier S, Vie V, Paboeuf G, Hennequin D, Perato S, De Giorgi M, Sinicropi MS, Sopkova-De Oliveira Santos J, Voisin-Chiret AS, Malzert-Freon A. De Pascale M, et al. ChemMedChem. 2020 Jan 7;15(1):136-154. doi: 10.1002/cmdc.201900542. Epub 2019 Nov 26. ChemMedChem. 2020. PMID: 31743599 Free article.
73 results