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The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity.
Ho P, Melms JC, Rogava M, Frangieh CJ, Poźniak J, Shah SB, Walsh Z, Kyrysyuk O, Amin AD, Caprio L, Fullerton BT, Soni RK, Ager CR, Biermann J, Wang Y, Khosravi-Maharlooei M, Zanetti G, Mu M, Fatima H, Moore EK, Vasan N, Bakhoum SF, Reiner SL, Bernatchez C, Sykes M, Mace EM, Wucherpfennig KW, Schadendorf D, Bechter O, Shah P, Schwartz GK, Marine JC, Izar B. Ho P, et al. Among authors: soni rk. Cancer Cell. 2023 Jul 10;41(7):1207-1221.e12. doi: 10.1016/j.ccell.2023.05.014. Epub 2023 Jun 15. Cancer Cell. 2023. PMID: 37327789
Tbc1d10c is a selective, constitutive suppressor of the CD8 T-cell anti-tumor response.
Cohen AO, Woo SH, Zhang J, Cho J, Ruiz ME, Gong J, Du R, Yarygina O, Jafri DZ, Bachelor MA, Finlayson MO, Soni RK, Hayden MS, Owens DM. Cohen AO, et al. Among authors: soni rk. Oncoimmunology. 2022 Nov 2;11(1):2141011. doi: 10.1080/2162402X.2022.2141011. eCollection 2022. Oncoimmunology. 2022. PMID: 36338148 Free PMC article.
Small-molecule allosteric inhibitors of GPX4.
Liu H, Forouhar F, Lin AJ, Wang Q, Polychronidou V, Soni RK, Xia X, Stockwell BR. Liu H, et al. Among authors: soni rk. Cell Chem Biol. 2022 Dec 15;29(12):1680-1693.e9. doi: 10.1016/j.chembiol.2022.11.003. Epub 2022 Nov 23. Cell Chem Biol. 2022. PMID: 36423641 Free PMC article.
A target discovery pipeline identified ILT3 as a target for immunotherapy of multiple myeloma.
Di Meo F, Iyer A, Akama K, Cheng R, Yu C, Cesarano A, Kurihara N, Tenshin H, Aljoufi A, Marino S, Soni RK, Roda J, Sissons J, Vu LP, Guzman M, Huang K, Laskowski T, Broxmeyer HE, Roodman DG, Perna F. Di Meo F, et al. Among authors: soni rk. Cell Rep Med. 2023 Jul 18;4(7):101110. doi: 10.1016/j.xcrm.2023.101110. Cell Rep Med. 2023. PMID: 37467717 Free PMC article.
An integrated toolkit for human microglia functional genomics.
Haq I, Ngo JC, Roy N, Pan RL, Nawsheen N, Chiu R, Zhang Y, Fujita M, Soni RK, Wu X, Bennett DA, Menon V, Olah M, Sher F. Haq I, et al. Among authors: soni rk. Stem Cell Res Ther. 2024 Apr 10;15(1):104. doi: 10.1186/s13287-024-03700-9. Stem Cell Res Ther. 2024. PMID: 38600587 Free PMC article.
Harnessing transcriptionally driven chromosomal instability adaptation to target therapy-refractory lethal prostate cancer.
Dhital B, Santasusagna S, Kirthika P, Xu M, Li P, Carceles-Cordon M, Soni RK, Li Z, Hendrickson RC, Schiewer MJ, Kelly WK, Sternberg CN, Luo J, Lujambio A, Cordon-Cardo C, Alvarez-Fernandez M, Malumbres M, Huang H, Ertel A, Domingo-Domenech J, Rodriguez-Bravo V. Dhital B, et al. Among authors: soni rk. Cell Rep Med. 2023 Feb 21;4(2):100937. doi: 10.1016/j.xcrm.2023.100937. Epub 2023 Feb 13. Cell Rep Med. 2023. PMID: 36787737 Free PMC article.
175 results