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Interactions between mitoNEET and NAF-1 in cells.
Karmi O, Holt SH, Song L, Tamir S, Luo Y, Bai F, Adenwalla A, Darash-Yahana M, Sohn YS, Jennings PA, Azad RK, Onuchic JN, Morcos F, Nechushtai R, Mittler R. Karmi O, et al. Among authors: song l. PLoS One. 2017 Apr 20;12(4):e0175796. doi: 10.1371/journal.pone.0175796. eCollection 2017. PLoS One. 2017. PMID: 28426722 Free PMC article.
NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth.
Sohn YS, Tamir S, Song L, Michaeli D, Matouk I, Conlan AR, Harir Y, Holt SH, Shulaev V, Paddock ML, Hochberg A, Cabanchick IZ, Onuchic JN, Jennings PA, Nechushtai R, Mittler R. Sohn YS, et al. Among authors: song l. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14676-81. doi: 10.1073/pnas.1313198110. Epub 2013 Aug 19. Proc Natl Acad Sci U S A. 2013. PMID: 23959881 Free PMC article.
The Fe-S cluster-containing NEET proteins mitoNEET and NAF-1 as chemotherapeutic targets in breast cancer.
Bai F, Morcos F, Sohn YS, Darash-Yahana M, Rezende CO, Lipper CH, Paddock ML, Song L, Luo Y, Holt SH, Tamir S, Theodorakis EA, Jennings PA, Onuchic JN, Mittler R, Nechushtai R. Bai F, et al. Among authors: song l. Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3698-703. doi: 10.1073/pnas.1502960112. Epub 2015 Mar 11. Proc Natl Acad Sci U S A. 2015. PMID: 25762074 Free PMC article.
Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells.
Holt SH, Darash-Yahana M, Sohn YS, Song L, Karmi O, Tamir S, Michaeli D, Luo Y, Paddock ML, Jennings PA, Onuchic JN, Azad RK, Pikarsky E, Cabantchik IZ, Nechushtai R, Mittler R. Holt SH, et al. Among authors: song l. J Cell Sci. 2016 Jan 1;129(1):155-65. doi: 10.1242/jcs.178293. Epub 2015 Nov 30. J Cell Sci. 2016. PMID: 26621032 Free PMC article.
Breast cancer tumorigenicity is dependent on high expression levels of NAF-1 and the lability of its Fe-S clusters.
Darash-Yahana M, Pozniak Y, Lu M, Sohn YS, Karmi O, Tamir S, Bai F, Song L, Jennings PA, Pikarsky E, Geiger T, Onuchic JN, Mittler R, Nechushtai R. Darash-Yahana M, et al. Among authors: song l. Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):10890-5. doi: 10.1073/pnas.1612736113. Epub 2016 Sep 12. Proc Natl Acad Sci U S A. 2016. PMID: 27621439 Free PMC article.
NEET Proteins: A New Link Between Iron Metabolism, Reactive Oxygen Species, and Cancer.
Mittler R, Darash-Yahana M, Sohn YS, Bai F, Song L, Cabantchik IZ, Jennings PA, Onuchic JN, Nechushtai R. Mittler R, et al. Among authors: song l. Antioxid Redox Signal. 2019 Mar 10;30(8):1083-1095. doi: 10.1089/ars.2018.7502. Epub 2018 Mar 29. Antioxid Redox Signal. 2019. PMID: 29463105 Free PMC article. Review.
The anti-apoptotic proteins NAF-1 and iASPP interact to drive apoptosis in cancer cells.
Iosub-Amir A, Bai F, Sohn YS, Song L, Tamir S, Marjault HB, Mayer G, Karmi O, Jennings PA, Mittler R, Onuchic JN, Friedler A, Nechushtai R. Iosub-Amir A, et al. Among authors: song l. Chem Sci. 2018 Nov 20;10(3):665-673. doi: 10.1039/c8sc03390k. eCollection 2019 Jan 21. Chem Sci. 2018. PMID: 30774867 Free PMC article.
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