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Discovery of Potent, Selective, and Orally Bioavailable Estrogen-Related Receptor-γ Inverse Agonists To Restore the Sodium Iodide Symporter Function in Anaplastic Thyroid Cancer.
Kim J, Song J, Ji HD, Yoo EK, Lee JE, Lee SB, Oh JM, Lee S, Hwang JS, Yoon H, Kim DS, Lee SJ, Jeong M, Lee S, Kim KH, Choi HS, Lee SW, Park KG, Lee IK, Kim SH, Hwang H, Jeon YH, Chin J, Cho SJ. Kim J, et al. Among authors: song j. J Med Chem. 2019 Feb 28;62(4):1837-1858. doi: 10.1021/acs.jmedchem.8b01296. Epub 2019 Feb 4. J Med Chem. 2019. PMID: 30657313
A Novel Orally Active Inverse Agonist of Estrogen-related Receptor Gamma (ERRγ), DN200434, A Booster of NIS in Anaplastic Thyroid Cancer.
Singh TD, Song J, Kim J, Chin J, Ji HD, Lee JE, Lee SB, Yoon H, Yu JH, Kim SK, Yoon GS, Hwang H, Lee HW, Oh JM, Lee SW, Lee J, Choi HS, Na SY, Choi WI, Park YJ, Song YS, Kim YA, Lee IK, Cho SJ, Jeon YH. Singh TD, et al. Among authors: song j, song ys. Clin Cancer Res. 2019 Aug 15;25(16):5069-5081. doi: 10.1158/1078-0432.CCR-18-3007. Epub 2019 Apr 22. Clin Cancer Res. 2019. PMID: 31010838
An orally available inverse agonist of estrogen-related receptor gamma showed expanded efficacy for the radioiodine therapy of poorly differentiated thyroid cancer.
Kim J, Hwang H, Yoon H, Lee JE, Oh JM, An H, Ji HD, Lee S, Cha E, Ma MJ, Kim DS, Lee SJ, Kadayat TM, Song J, Lee SW, Jeon JH, Park KG, Lee IK, Jeon YH, Chin J, Cho SJ. Kim J, et al. Among authors: song j. Eur J Med Chem. 2020 Nov 1;205:112501. doi: 10.1016/j.ejmech.2020.112501. Epub 2020 Jul 14. Eur J Med Chem. 2020. PMID: 32758860
Targeted Inhibition of the NCOA1/STAT6 Protein-Protein Interaction.
Lee Y, Yoon H, Hwang SM, Shin MK, Lee JH, Oh M, Im SH, Song J, Lim HS. Lee Y, et al. Among authors: song j. J Am Chem Soc. 2017 Nov 15;139(45):16056-16059. doi: 10.1021/jacs.7b08972. Epub 2017 Nov 1. J Am Chem Soc. 2017. PMID: 29090910
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