Sonawane V - Search Results

1

Prostate Apoptosis Response-4 (Par-4): A Novel Target in Pyronaridine-Induced Apoptosis in Glioblastoma (GBM) Cells.

Ghosalkar J, Sonawane V, Pisal T, Achrekar S, Pujari R, Chugh A, Shastry P, Joshi K. Ghosalkar J, et al. Among authors: sonawane v. Cancers (Basel). 2022 Jun 29;14(13):3198. doi: 10.3390/cancers14133198. Cancers (Basel). 2022. PMID: 35804970 Free PMC article.

2

Cyclin-dependent kinase inhibitor, P276-00 induces apoptosis in multiple myeloma cells by inhibition of Cdk9-T1 and RNA polymerase II-dependent transcription.

Manohar SM, Rathos MJ, Sonawane V, Rao SV, Joshi KS. Manohar SM, et al. Among authors: sonawane v. Leuk Res. 2011 Jun;35(6):821-30. doi: 10.1016/j.leukres.2010.12.010. Epub 2011 Jan 8. Leuk Res. 2011. PMID: 21216463

3

A novel inhibitor of hypoxia-inducible factor-1α P3155 also modulates PI3K pathway and inhibits growth of prostate cancer cells.

Manohar SM, Padgaonkar AA, Jalota-Badhwar A, Sonawane V, Rathos MJ, Kumar S, Joshi KS. Manohar SM, et al. Among authors: sonawane v. BMC Cancer. 2011 Aug 5;11:338. doi: 10.1186/1471-2407-11-338. BMC Cancer. 2011. PMID: 21819554 Free PMC article.

4

P7170, a novel inhibitor of mTORC1/mTORC2 and Activin receptor-like Kinase 1 (ALK1) inhibits the growth of non small cell lung cancer.

Venkatesha VA, Joshi A, Venkataraman M, Sonawane V, Bhatia D, Tannu P, Bose J, Choudhari S, Srivastava A, Pandey PK, Lad VJ, Sangana R, Ahmed T, Damre A, Deore V, Sahu B, Kumar S, Sharma S, Agarwal VR. Venkatesha VA, et al. Among authors: sonawane v. Mol Cancer. 2014 Dec 2;13:259. doi: 10.1186/1476-4598-13-259. Mol Cancer. 2014. PMID: 25466244 Free PMC article.

5

Cink4T, a quinazolinone-based dual inhibitor of Cdk4 and tubulin polymerization, identified via ligand-based virtual screening, for efficient anticancer therapy.

Sonawane V, Mohd Siddique MU, Jadav SS, Sinha BN, Jayaprakash V, Chaudhuri B. Sonawane V, et al. Eur J Med Chem. 2019 Mar 1;165:115-132. doi: 10.1016/j.ejmech.2019.01.011. Epub 2019 Jan 10. Eur J Med Chem. 2019. PMID: 30665142

6

Quinazoline derivatives as selective CYP1B1 inhibitors.

Mohd Siddique MU, McCann GJ, Sonawane VR, Horley N, Gatchie L, Joshi P, Bharate SB, Jayaprakash V, Sinha BN, Chaudhuri B. Mohd Siddique MU, et al. Among authors: sonawane vr. Eur J Med Chem. 2017 Apr 21;130:320-327. doi: 10.1016/j.ejmech.2017.02.032. Epub 2017 Feb 16. Eur J Med Chem. 2017. PMID: 28259840

7

Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in CYP1A1-overexpressing breast cancer cells.

Sharma R, Williams IS, Gatchie L, Sonawane VR, Chaudhuri B, Bharate SB. Sharma R, et al. Bioorg Med Chem. 2018 Dec 15;26(23-24):6076-6086. doi: 10.1016/j.bmc.2018.11.013. Epub 2018 Nov 10. Bioorg Med Chem. 2018. PMID: 30448188

8

Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines.

Horley NJ, Beresford KJ, Chawla T, McCann GJ, Ruparelia KC, Gatchie L, Sonawane VR, Williams IS, Tan HL, Joshi P, Bharate SS, Kumar V, Bharate SB, Chaudhuri B. Horley NJ, et al. Among authors: sonawane vr. Eur J Med Chem. 2017 Mar 31;129:159-174. doi: 10.1016/j.ejmech.2017.02.016. Epub 2017 Feb 9. Eur J Med Chem. 2017. PMID: 28222316

9

Identification of Potent and Selective CYP1A1 Inhibitors via Combined Ligand and Structure-Based Virtual Screening and Their in Vitro Validation in Sacchrosomes and Live Human Cells.

Joshi P, McCann GJP, Sonawane VR, Vishwakarma RA, Chaudhuri B, Bharate SB. Joshi P, et al. J Chem Inf Model. 2017 Jun 26;57(6):1309-1320. doi: 10.1021/acs.jcim.7b00095. Epub 2017 May 22. J Chem Inf Model. 2017. PMID: 28489395

10

CYP enzymes, expressed within live human suspension cells, are superior to widely-used microsomal enzymes in identifying potent CYP1A1/CYP1B1 inhibitors: Identification of quinazolinones as CYP1A1/CYP1B1 inhibitors that efficiently reverse B[a]P toxicity and cisplatin resistance.

Sonawane VR, Siddique MUM, Gatchie L, Williams IS, Bharate SB, Jayaprakash V, Sinha BN, Chaudhuri B. Sonawane VR, et al. Eur J Pharm Sci. 2019 Apr 1;131:177-194. doi: 10.1016/j.ejps.2019.02.016. Epub 2019 Feb 15. Eur J Pharm Sci. 2019. PMID: 30776468

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